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“All signs require further investigation and confirmation through formal epidemiological studies,” fitness officials said. “When one formula detects a signal, other protective tracking formulas are checked to validate whether the signal poses a real challenge with the vaccine or whether it can be done. “We think it has no clinical relevance. ” Moderna’s bivalent vaccine did not cause the same initial signal, fitness officials said, and no adjustments were made to vaccine recommendations for any age group.
In a statement, Pfizer and BioNTech pointed to the fact that neither the corporations nor the FDA or CDC have discovered any potential signs of protection outside the VSD system and that, to date, corporations have observed a “lower number of reported ischemic cases. “strokes. “” after a stimulus with the Pfizer bivalent vaccine compared with overall incidence rates in the older population.
“With millions of doses of the original and adapted Pfizer-BioNTech COVID-19 bivalent vaccine Omicron BA. 4/BA. 5 administered worldwide, the risk-benefit profile of our vaccines remains for all legal indications and age groups,” the corporations said.
Health officials will hold a Jan. 26 town hall meeting, which anyone can watch online, to discuss COVID-19 vaccines and boosters, and review knowledge of CDC and FDA research into the imaginable but unlikely link between the Pfizer recall and stroke for older adults.
Anyone can have a stroke, but there is a threat of having twice as much for every decade of life after age 55, according to Johns Hopkins Medicine. COVID-19 severe and accounted for more than 81% of all COVID-19 deaths.
The reinforcements have been mainly for the elderly population in the prevention of serious illness and death. An Oct. 7 report from the U. S. Department of Health and Human ServicesThe U. S. Food and Drug Administration found that COVID-19 vaccines were linked to about 650,000 fewer hospitalizations and 300,000 fewer deaths among seniors and others enrolled in Medicare in 2021.
Updated boosters are available to anyone 6 months and older in the United States. Here’s what we know about them.
Bivalent formulations manufactured through Moderna and Pfizer-BioNTech target the “original” edition of COVID-19, as well as the BA. 4 and BA. 5 subvariants of omicron. Both are available for adults and children from 6 months. .
Although BA. 4 and BA. 5 are no longer the disease-causing subvariants in the United States (XBB. 1. 5 is about to replace BQ. 1 and BQ. 1. 1), some laboratory studies recommend that bivalent boosters will be sufficient to neutralize XBB. 1. 5 and prevent serious disease. And real-world data confirms the efficacy of new boosters from the original COVID-19 vaccine formulations.
New real-world knowledge from Israel confirms that new COVID-19 vaccines formulated to act in the opposite of the omicron variant are effective in preventing other people from going to the hospital, according to findings published via The Lancet. The study, which has yet to be published peer-reviewed, included data from more than 600,000 people aged 65 and older.
This real-world knowledge confirms previous data from the CDC, which found that, as of November 2022, hospitalization rates per month for adults vaccinated but not receiving an updated booster were 2. 7 times higher than those for adults who received a new booster. Hospitalization rate for unvaccinated adults was 16 times higher than for adults who gained a new booster.
While there is now positive knowledge, the lack of genuine knowledge at the beginning of the bivalent recall crusade caused some researchers to stop. points to the BA. 1 edition of omicron instead of BA. 4/BA. 5. In addition, there were studies in mice on the formula BA. 4/BA. 5. This technique was unprecedented in the past in the COVID-19 vaccination campaign, yet fitness officials say it’s not too far from how we approve flu vaccines. Each year, the flu vaccine is changed with a strain that is considered the most productive target. And the new COVID-19 boosters don’t introduce new ingredients for the vaccine either. .
“Bivalent and multivalent vaccines are very common, and modifying a vaccine to come with other virus strains does not require converting other ingredients,” FDA Commissioner Dr. Robert M. Califf said in a tweet in August. in reviewing strain adjustments in vaccines, such as the annual flu vaccine. “
Adults who have been vaccinated against COVID-19, but have not yet gained a booster, can get a booster dose of Novavax. No matter which vaccine won first: Pfizer, Moderna, Johnson
Learn about the Novavax vaccine here.
Updated mRNA boosters (from Pfizer and Moderna) are legal through the FDA for adults who have passed at least two months since their last vaccine dose, either a booster or a number one series. It doesn’t matter which vaccine you originally received, and it doesn’t matter which logo you choose now. Moderna’s new booster, like its previous vaccine, has a higher dose (50 micrograms) than Pfizer’s (30 micrograms).
For infants, toddlers, and preschoolers who are eligible for smaller doses of updated formulas, it’s a little different. Children 6 months to five years of age who have won the number one series of Moderna cannot get an updated vaccine. dose of Moderna until at least two months after your injection at the moment. Children 6 months through four years of age who have started the number one Pfizer series are likely to get the bivalent vaccine as the third dose, rather than the “original” third dose. Children at this age, the organization that has already won 3 doses of Pfizer is not eligible for an updated booster at this time.
If you are 18 or older and have previously been vaccinated in the pandemic but have not yet gained a booster, you can get vaccinated with Novavax at least six months after completing your number one series if you prefer to an mRNA vaccine.
If you are sixty or older, or even if you are fifty, the recommendation of medical experts is clear: get the updated reminder as soon as possible. Older adults are more vulnerable to severe illness and death from COVID-19. If you’re younger and have a condition that makes you more vulnerable to serious illnesses, such as diabetes, core disease, etc. , you may also benefit from increased coverage for serious illnesses.
Health officials encouraged everyone to update their boosters, and Moderna and Pfizer-BioNTech’s legal formulas for children as young as 5 (in recent months, not last year) aren’t as straightforward as for high-risk adults or others who are several months old. far from his last episode of COVID-19.
At a meeting of the CDC’s clinical advisory panel, a committee that meets before the CDC recommends a vaccine, some members expressed fear that other people would be better off waiting more than two months between their last shot and this new booster, especially others who have recently had COVID-19 and still have superior immunity. (In its general rules about vaccines, the CDC states that other people can wait 3 months before getting vaccinated if they outgrow COVID-19. )
And myocarditis is rare worldwide, younger men and adolescents seem to be at higher risk after vaccination and waiting longer between vaccine doses reduces this threat.
From an immune reaction perspective, some infectious disease doctors have advised waiting 4 to 6 months between your last COVID-19 infection or vaccine to get the most out of the new booster. Fauci told PBS that if you recently tested positive for COVID-19, “wait about 3 months, at least 3 months from the time you had a previous infection” before receiving the new reminder. Fauci added that because he had COVID-19 in mid to last June, he was waiting until the end of September to be boosted.
Fauci ended up getting his encore on The Late Show With Stephen Colbert in early October.
But individual immunity is only one piece of the puzzle, when it comes to a respiratory virus as contagious as COVID-19. People who only have very mild symptoms of being bloodless or allergic can still transmit an infection to their maximum vulnerability. circle of family or friends.
“Even if you’re on the low-risk side yourself, you’ll have a circle of family and friends you’ll see,” said Dr. Ashish Jha, coordinator of the White House COVID-19 response team. on Andy Slavitt’s podcast in October, as reported via CNBC.
“You don’t have to be the user who provides it to your grandmother. “
Dr. Jayne Morgan, executive director of Piedmont Healthcare’s COVID Task Force, said it’s vital to get a reminder now so we can “stem the tide” of the pandemic.
“You need to have this booster while omicron is circulating. The goal of releasing the booster now is that we can avoid chasing this variant,” Morgan said, adding that it’s unclear what variants or subvariants there will be in our future, and whether (or to what extent) they will escape our coverage from vaccines, infections and treatments.
Vaccines and boosters have been shown to be especially effective in preventing serious illness in the elderly. An Oct. 7 report from the U. S. Department of Health and Human Services. Seniors and others enrolled in Medicare in 2021. More than 81% of COVID-19 deaths occur in others over age 65, according to the CDC.
You can use the Vaccines. gov vaccine search site to find an up-to-date vaccine near you. When opting for your upgraded booster from Pfizer-BioNTech or Moderna, be sure to choose the snapshot that says “Newly Authorized Bivalent. “” in ambitious text. Vaccines in the primary series, or the first two doses, are still available to others who have not yet received a vaccine.
Smaller doses of the original vaccines are also available for children up to 6 months of age. For those who get the Novavax booster, you can place it under “Primary Vaccines”.
Yes, according to CDC. Il, there is no waiting era between seasonal flu vaccine and COVID-19 vaccines.
To date, the existing flu season has been the most severe since the 2010-2011 flu season.