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Joe Biden tested positive for covid on Saturday, less than a week after the president returned to work following his coronavirus diagnosis in late July.
“The president has not experienced any recurrence of symptoms and continues to feel quite well,” the White House doctor said in a July 30 note. “This being the case, there is no explanation as to why to resume treatment at this time, but A close observation dazzlingly continues. “
Biden’s Covid boomerang is the latest case of high-profile “rebound” among those who have taken Paxlovid, an antiviral drug from Pfizer, after White House medical adviser Dr. Anthony Fauci in June.
Here’s what you want to know about Covid and Paxlovid rebound cases.
How unusual are bounce instances with Paxlovid?
The FDA approved Paxlovid for emergency use in December. Early studies suggest that between 1 and 6% of other people experience “rebound” symptoms towards the end of their initial covid journey, between days 10 and 14 from the initial positive covid test. they are not new Covid infections.
According to the CDC, rebound symptoms tend to be milder and are unlikely to result in hospitalization. The company says there is no evidence that more Paxlovid is needed to recover cases, noting that “a brief reversal of symptoms could be part of the herbal story of” covid.
Some doctors, relying heavily on anecdotal evidence so far, claim that rebound cases are more frequent, with rates between 20 and 40 percent.
“I think it’s predictable,” Dr. Jonathan Reiner of George Washington University wrote on Twitter Saturday about the president’s new diagnosis. “Previous knowledge suggesting that Paxlovid positivity ‘bounces’ in less than a single digit is outdated. “
Do bounce instances mean paxlovid isn’t working?
Health experts say Paxlovid is still very effective in preventing other high-risk people from entering the hospital.
“Paxlovid works very well to save you from a serious illness, rebound or no bounce, and that’s why he introduced it, and that’s why the president took it,” White House COVID-19 reaction coordinator Dr. Ashish Jha said in July when Ashlovid Jha said in July, when Biden first contracted the coronavirus.
Studies show that it can pose a risk of hospitalization and death in the most vulnerable Covid patients by nearly 90 percent, according to Yale.
A late-stage clinical trial found that Paxlovid reduced the threat of hospitalization or death by 89%. These figures were sent to the U. S. Food and Drug Administration. The U. S. Food and Drug Administration (FDA) last year before the drug got emergency approval.
“The message I need to convey is that if you’re eligible and if you’re at risk, I think it’s a phenomenal drug that can make a difference in keeping other people out of the hospital and not needing to be hospitalized. ” Dr. Sabrina Assoumou of Boston Medical Center told NBC Boston.
There is initial evidence that Paxlovid, which is recently approved for the elderly and other high-risk groups, has no statistical effect on covid case hospitalizations among young and low-risk people, who have little chance of being hospitalized anyway. Pfizer’s trials of the drug found no difference in young, unvaccinated, low-risk people, as an Israeli study did.
What’s in it for Paxlovid and bounce cases?
Doctors say the next maximum vital areas to examine are the maximum productive time to prescribe Paxlovid, how its effectiveness might adapt to changing variants of covid, and whether doctors deserve to adopt a multi-drug cocktail treatment regimen, as they do with others. virus such as HIV.