Update: Severe respiratory disease related to Middle East Respiratory Syndrome coronavirus (MERS-CoV)

In consultation with WHO, the review era for the evaluation of MERS-CoV infection in others expanding severe acute respiratory disease decreased a few days later from the Arabian Peninsula or neighbouring countries has been prolonged from 10 days to 14 days later. Severe acute respiratory disease decreased within 14 days of maruca of the Arabian Peninsula or neighboring countries deserve to be assessed according to existing rules (available in http://www.cdc.gov/coronavirus/mers/case-def.html). People with unexplained respiratory diseases that meet the “patient under investigation” criteria deserve to be informed without delay to the CDC through state and local fitness services. People with a severe acute respiratory disease that are nearby (of a symptomatic ler that has developed fever and acute respiratory disease within 14 days of being born in the Arabian Peninsula or neighboring countries) would likely be considered as for a MERS evaluation. Cov. In addition, the CDC recommends that groups of severe acute respiratory diseases be investigated and, if an apparent etiology is not identified, local fitness officers are informed and MERS-CoV screenings are performed if they are performed.

To increase the likelihood of detecting MERS-CoV, the CDC recommends taking samples from other sites (for example, a nasopharyngeal swab and a decreased breathing sample, such as sputum, bronchoalveolar washing, bronchial washing, or tracheal suction). Samples deserve to be taken at other times after the onset of symptoms, if possible. Lower breathing samples deserve to be a priority for PCR collection and analysis; Stool samples may also be taken. Samples deserve to be taken with appropriate infection precautions (available in http://www.cdc.gov/coronavirus/mers/case-def.html).

Sample testing for MERS-CoV is recently being carried out at the CDC. The FDA issued a U.S. on June 5, 2013 to authorize the use of the NEW 2012 CDC 2012 coronavirus (NCV-2-12 rRT-PCR) as opposed to transcription control to verify MERS-CoV in the airways, blood and stool samples. This U.S. is mandatory because there are currently no FDA-approved controls that identify MERS-CoV in clinical samples. Verification will be implemented in Lab Response Network (LRN) lab operations in all 50 states over the next 50 weeks. Updated data on labs with the ability to perform MERS checks with NCV-2-12 rRT-PCR verification will be provided in the CDC MERS (http://www.cdc.gov/coronavirus/mers/case-def.html).

In consultation with WHO, the definition of a probable case of MERS-CoV infection has been updated to also include others with severe acute respiratory disease with no known etiology with an epidemiological link to a demonstrated case of MERS-CoV infection. Until the transmission characteristics of MERS-CoV are better understood, patients under investigation and likely and proven cases deserve to be controlled with standard precautions for fitness, tactile and air-borne services. As the data becomes available, those recommendations will be reevaluated and updated as needed.

Recommendations and recommendations on case definitions, infection (including the use of non-public protective equipment), case investigations and pattern collection and pattern testing can be obtained on the CDC MERS online page (http://www.cdc.gov/ coronavirus/mers/index.html). The MERS online page includes the latest data and recommendations, which are likely to change. State and local center gyms with questions deserve to contact the CDC Emergency Operations Center (770-488-7100).

The countries believed to be located in or near the Arabian Peninsula are Bahrain, Iraq, Iran, Israel, Jordan, Kuwait, Lebanon, Oman, the Palestinian Territories, Qatar, Saudi Arabia, Syria, the United Arab Emirates and Yemen. Close contacts are explained as 1) people who have provided care to the patient, adding caregivers and members of the family circle, or who have had other similar physical contact, or 2) people who have remained in the same position (e.g. visited) as a patient while the patient is sick.

Weekly morbidity and mortality report. 2013; (23): 480-483. © 2013 Centers for Disease Control and Prevention (CDC)

Division of Global Quarantine and Migration, Division of Health Care Quality Promotion, National Center for Emerging Infectious Diseases and Zoonotic Diseases; Office of Civil Protection and Emergency Response, National Institute of Occupational Safety and Health; Div of Global Health Protection (proposed), Center for Global Health; Division of Viral Diseases, National Center for Immunization and Respiratory Diseases; Paul A. Gasta-aduy, MD Agent EIS, CDC. [email protected], 770-488-7100.

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