LONDON – British scientists are starting a small study comparing the functioning of two experimental coronavirus vaccines when inhaled through other people or injected.
In a statement published Monday, researchers from Imperial College London and the University of Oxford said that a trial involving another 30 people would check for vaccines evolved through the two establishments when participants inhaled droplets into their mouths, directly aimed at their respiratory systems.
Broader studies on The Imperial and Oxford vaccines are already underway, however, this test aims to see if vaccines can be more effective if inhaled.
“We have evidence that administering flu shots through a nasal spray can help others with influenza reduce transmission of the disease,” said Dr Chris Chiu of Imperial, who leads the research. He warned that this could also be the case with COVID-19.
“We read about whether direct airway focus can provide an effective reaction to a vaccine injected into the muscle,” Chiu said in a statement.
The study is recently recruiting participants between the ages of 18 and 55 and hopes to start vaccinating others in London in the coming weeks.
Previous studies have shown that inhaled vaccines require lower doses than injections, possibly extending limited stocks.
“It’s possible that an organization has the right vaccine with the delivery approach, and only trials like this can tell us that,” said Robin Shattock, who is leading the progression of the Imperial vaccine.
The imperial vaccine uses artificial strands of genetic code in the virus. Once injected into the muscle, the frame cells themselves are guilty of making copies of a protein that is biza in the coronavirus, which is expected to cause an immune reaction so that the framework can fight. of any long-term infection with COVID-19.
By comparison, the Oxford vaccine uses an innocent virus, a chimpanzee bloodless virus, designed not to spread, to bring complex coronavirus protein to the body, causing an immune response.
Last week, Oxford temporarily suspended its large-scale vaccination tests after a player in the UK reported severe neurological symptoms; restarted on Sunday.
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