A foreign study of about 99 million people showed the known serious side effects of the COVID-19 vaccine. He also pointed to a possible link between the first dose of the Moderna vaccine and a low risk of neurological disease. Social media posts about the study were approved. about data on the benefits of vaccines and the rarity of side effects.
More than a billion doses of COVID-19 vaccines have been administered in EE. UU. se and only very few protective considerations have emerged. The vast majority of people experience only minor, transient side effects, such as pain at the injection site. , fatigue, headache or muscle aches, or no side effects at all. As the Centers for Disease Control and Prevention has stated, those vaccines “have been and will continue to be subject to the broadest protective oversight in U. S. history. “
A small number of severe allergic reactions called anaphylaxis, which are expected with any vaccine, have occurred with both legal and approved COVID-19 vaccines. Fortunately, such reactions are rare, occur within minutes of inoculation, and can be treated. According to the CDC, about five out of every million vaccinated people experienced anaphylaxis after the COVID-19 vaccine.
To ensure that severe allergic reactions can be known and treated, all other people who receive a vaccine will be observed for 15 minutes after receiving the injection, as well as anyone who has suffered anaphylaxis or had an immediate allergic reaction to a vaccine or injection in the past. be monitored for part of an hour. People who have had a severe allergic reaction to a previous dose or to any of the ingredients in the vaccine will not be able to get vaccinated. In addition, those who do not receive one type of COVID-19 vaccine will be monitored for 30 minutes after receiving any other type of vaccine. vaccine.
It’s true that the Pfizer/BioNTech and Moderna mRNA vaccines can rarely cause inflammation of the core muscle (myocarditis) or the surrounding lining (pericarditis), especially in adolescents and young adults.
Based on data collected through August 2021, reporting rates for any of the conditions in the U. S. are as high as those reported in the U. S. The U. S. prevalence rates are highest among males aged 16 to 17 years after the second dose (105. 9 cases per million doses of the Pfizer/BioNTech vaccine), followed by 12- to 15-year-olds (70. 7 cases consistent with one million). The rate for older men ages 18 to 24 was 52. 4 and 56. 3 times per million doses of the Pfizer/BioNTech and Moderna vaccines, respectively.
Health officials said cases of vaccine-related myocarditis and pericarditis are rare and that the benefits of vaccination still outweigh the risks. Preliminary evidence suggests that these cases of myocarditis are less severe than typical cases. The CDC also noted that most of the patients treated “responded well to medications and rest and felt better quickly. “
The Johnson Vaccine
According to the CDC, TTS occurred in about four other people with millions of doses administered. At the beginning of April, the syndrome had manifested itself in 60 cases, adding nine deaths, after more than 18. 6 million doses of the J vaccine.
The J vaccine
Link to this
COVID-19 vaccines, like all vaccines and other medical products, cause side effects, adding serious side effects in rare cases. The vaccines were given to other people from a new virus that has killed millions of people around the world and likely would have killed millions more had it not been for the advent of vaccines. There is broad consensus among experts and government fitness agencies that the benefits of the COVID-19 vaccine outweigh the risks.
Researchers have examined the protection of COVID-19 vaccines and continue to do so. A study published Feb. 12 in the journal Vaccine reported on a foreign organization of more than 99 million people getting COVID-19 vaccines, usually locating links to rare side effects. The study focused largely on the Pfizer/BioNTech and Moderna vaccines, which have been widely administered in the U. S. The AstraZeneca vaccine, which has never been legal in the U. S. , has been used in the U. S. U. S.
“What we take away is that Covid-19 vaccination campaigns have been very effective in preventing severe disease,” Anders Hviid, co-author of the study and head of the epidemiology studies branch at the Statens Serum Institut in Denmark, told us in a statement. . e-mail. ” The few serious side effects we’ve noticed in this and other studies are rare. “
Many popular social media posts shared the effects of the study, some without specifying that known fitness disorders are rare, that most are not new, and that vaccines have shown benefits. Several articles contained unsubstantiated claims, claiming or implying that other people had not won. vaccines, that the threats outweighed the benefits, or that the threat of rare side effects was greater than reported in the study.
“Hundreds of millions of people have been used as lab rats and now there is no longer any denying the fact that WE ALREADY KNOW,” one popular article said, calling the vaccines “experimental” and “UNPROVEN. “headline of a New York Post article about the new study, which read, “COVID Vaccines Linked to Small Increases in Heart, Brain and Blood Disorders: Study. “
“This was imposed on other people who were almost not threatened by Covid,” read another widely read article. “This is absolutely unacceptable. ” The publication shared the newspaper’s statistics without mentioning that severe fitness disorders after vaccination were rare and that the threat varied depending on the type and dose of vaccine.
The vaccine study showed that the Moderna and Pfizer/BioNTech vaccines are linked in rare cases to myocarditis and pericarditis, conditions that involve inflammation of the central muscle and its mucosa. The rate of myocarditis was higher after the second dose of the Moderna vaccine. The risk of myocarditis, which is highest in men in their teens and early twenties, was known by tracking vaccine protection and was first reported in 2021. Based on existing evidence, according to the CDC, advantages of vaccination outweigh the threat of these situations. , which improves in most people after medical treatment and rest.
They showed relevant neurological and blood clotting disorders with the AstraZeneca vaccine. In the U. S. , those disorders were similar to those of the Johnson vaccine.
The study also found a possible new defense signal indicating a possible link between the first dose of the Moderna and AstraZeneca vaccines and rare neurological diseases. This included a link between first doses of the vaccines and acute disseminated encephalomyelitis, or ADEM, an autoimmune disease that causes inflammation of the brain and spinal cord.
Hviid noted that the researchers observed such neurological occasions after the first doses of either vaccine. “We haven’t noticed those signs after additional doses of those two Covid-19 vaccines, nor after one dose of the Pfizer/BioNTech vaccine that has been more widely used,” he said.
“We’re also talking about very rare events,” Hviid continued. “For example, the combination between the first dose of Moderna and acute inflammation of the brain and spine would, if causal, be a case consistent with 1. 75 million vaccine recipients. It was only thanks to the scale of our study that we were able to identify this small potential risk.
The vaccine study was based on national or regional fitness registries from eight countries whose institutions participate in the Global Vaccine Data Network, a foreign organization that studies vaccine safety. The researchers analyzed fitness results after approximately 184 million doses of the Pfizer/BioNTech vaccine, 36 million doses of the Moderna vaccine, and 23 million doses of the AstraZeneca vaccine.
The researchers focused on thirteen fitness situations that had a known link to vaccination or for which there was reason to investigate whether a link existed. To determine whether fitness disorders were related to vaccination, they compared the expected rates of fitness disorders, or the number of fitness events expected to occur based on baseline rates in the study regions, with the number of events they observed during the 42 days following vaccination.
“This study confirms the major side effects already detected and validated established in the previous literature,” Jeffrey S told us via email. Morris, chair of the department of biostatistics at the Perelman School of Medicine at the University of Pennsylvania, referring to the center’s rare diseases. related to the Moderna and Pfizer/BioNTech vaccines, as well as rare illnesses linked to the AstraZeneca and Johnson vaccines
Morris said the effects on ADEM (the rare autoimmune neurological disease linked to the first doses of the Moderna and AstraZeneca vaccines) “could be a new signal of protection. “
ADEM refers to inflammation of the brain and spinal cord, which occurs most often in children as a result of an infectious disease. It seems to improve suddenly and eventually, with a complete cure in many, though not all, cases.
After the first dose of the Moderna vaccine, the researchers observed seven cases of ADEM, when they were expecting two. As we said, Hviid calculated the rate of this side effect, if it turns out to be similar to vaccination, at 1 in 1. 75 million after the first dose of the Moderna vaccine.
The data shows “that this is actually an EXTREMELY rare adverse event,” Morris said, referring to ADEM. “It’s understandable, at this rate of occurrence, why it wouldn’t have been detected earlier and why a study with 99 million participants like this “is important to detect even the rarest serious adverse events that pose potential minority harm risks due to those vaccines. “
The study authors wrote that more studies on ADEM after COVID-19 vaccination are needed, stating that “the number of cases of this rare event was low and the confidence period wide, so the effects should be interpreted with caution and demonstrated in the long term. “studies. . . ” The authors also wrote that neurological events occurred at a much higher rate after COVID-19 than after COVID-19 vaccination.
The study means that “early warning systems are robust,” Marc Veldhoen, an immunologist at the João Lobo Antunes Institute of Molecular Medicine in Portugal, said in an article on X, formerly known as Twitter. “It’s not conceivable to avoid any adverse reaction, but it would possibly be conceivable to identify other people who are at higher risk. “
Identifying those that are most at risk for side effects can help doctors make decisions about which vaccines to propose and what disorders doctors look for in their patients.
Editor’s note: SciCheck articles that provide accurate fitness data and correct erroneous fitness data are made imaginable thanks to a grant from the Robert Wood Johnson Foundation. The Foundation has no control over FactCheck. org’s editorial decisions, and the perspectives expressed in our articles do not necessarily reflect those of the Foundation.
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