A drug used to cure a deadly viral disease in cats may be effective as a remedy for humans who oppose the new coronavirus, according to a study that can also lead to the progression of new treatments to treat COVID-19. research, published in the journal Nature Communications, the drug is effective at inhibiting viral replication in laboratory-grown cells inflamed with the new SARS-CoV-2 coronavirus.
“This drug is most likely for human paintings, so it encourages us to be an effective antiviral remedy for PATIENTS with COVID-19,” said Joanne Lemieux, professor of biochemistry at the University of Alberta. Scientists have noted that the drug interferes with the virus’s ability to reflect and may help end the infection. They said the drug is an inhibitor of safe-frame protease molecules, which are essential for many physical functions, and are not unusual targets for drugs that are meant to treat “everything from high blood pressure to cancer and HIV. “
According to scientists, the drug was first studied after the 2002-03 SARS pandemic, after which the protease inhibitor was developed through veterinary researchers who showed that it cures a deadly disease in cats. “We decided the three-dimensional shape of the protease with the drug in the pocket of the active site, showing the inhibition mechanism. This will allow us to expand even more effective drugs,” Lemieux said. The scientists said they planned to verify the drug’s modifications to make it even more adapted to the virus.
But, according to Lemieux, the existing drug shows enough antiviral action opposite SARS-CoV-2 to continue clinical trials. “In general, for a drug to be clinically tested, it must be confirmed in the laboratory and then tested in animal models. “Mr. Lemieux said. ” Because this drug has already been used to treat cats with coronavirus and is effective with little or no toxicity, it has already passed those steps and this allows us to move forward,” he added.
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