South Africa will launch clinical trials on a coronavirus vaccine developed in the United States with 2,900 volunteers this week, the time in Africa’s most affected country, lead researcher Shabir Madhi said Tuesday.
Known as NVX-CoV2373, the vaccine evolved through the US biotechnology company Novavax from the SARS-CoV-2 genetic series, the virus that causes COVID-19 disease.
It will be administered to the first volunteer in the randomized blind trial on Wednesday.
“It’s a two-dose program, and they get two vaccines or placebos…three weeks apart,” Professor Madhi of the University of Witwatersrand (Wits) in Johannesburg told the AFP.
With 589,886 cases and 11,982 deaths, South Africa ranks fifth in the world ranking of the most inflamed countries.
As the country also accounts for 20% of HIV infections internationally according to UNAIDS 2020 data, 240 medically sound HIV-positive adults will also participate in the clinical trial.
“We see how these vaccines work in HIV-positive populations, especially in South Africa, where they account for about 12 to 15% of the adult population,” Madhi said.
The University of Wits said studies of the Novavax vaccine in non-human primates have shown coverage opposed to coronavirus infection in the nostrils rather than coverage opposed to lung disease.
Funded through a $15 million grant from the Bill Foundation
In June, South Africa tested its first trial of a vaccine developed through the UK-based Oxford Jenner Institute.
Some 2,000 more people gained an injection of the vaccine known as ChAdOx1 nCoV-19 and 50 of the applicants were HIV positive.
[AFP]
Vanguard News Nigeria.
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