Researchers in Germany and Turkey have conducted research that smoking is linked to a greater threat of disease in coronavirus disease 2019 (COVID-19).
Systematic meta-analysis revealed that severe COVID-19 occurred between 1.5 and 2 times more in smokers and ex-smokers than in others who had never smoked.
Askin Gulsen (University of Luebeck, Germany) and his colleagues say the pandemic inspired others at risk of quitting smoking.
“It is very transparent that the pandemic era is an opportunity to quit smoking because of the option of finding worse clinical outcomes and headaches in patients with a history of smoking,” they write.
You must have a preprinted edition of the article on the medRxiv server, while the article is peer-reviewed.
Since the first cases of COVID-19 were known in Wuhan, China, which was defeated last year, the causal agent, acute respiratory syndrome severe coronavirus 2 (SARS-CoV-2), has swept worldwide and has been declared a pandemic worldwide.Organization of Health on 11 March 2020.
This highly contagious virus has inflamed more than 22 million people internationally and has caused more than 778,000 deaths.
COVID-19 is primarily a respiratory disease, with SARS-CoV-2 the pulmonary epithelium and causing viral pneumonia and acute respiratory misery syndrome, especially in elderly patients.
The most serious rates of disease and mortality are higher in the elderly population and among others with concomitant diseases, such as chronic obstructive pulmonary disease (COPD) and asthma.
Reports indicated that COVID-19 is making more serious progress in COPD patients.Since smoking plays a role in the pathogenesis of COPD, he and his colleagues cautioned that it may also be the progression of COVID-19 symptoms.
However, researchers say that a recent metainvestigation found that smoking did not increase the severity of COVID-19, this research included only five studies. Another metainvestigation that included more studies found an agreement between smoking and a growing severity of the disease.
“The other effects of the two meta-analysis create confusion about the smoking factor,” the team explains.
Based on these inconsistent findings, the researchers set out to determine whether smoking is related to the severity of COVID-19 using a systematic meta-analysis approach.
After searching the knowledge base for Google Scholar, PubMed, Web of Science, Embase and Scopus for clinical studies that met the inclusion criteria, they learned 16 studies published between December 2019 and April 15, 2020, with knowledge that it was held for 10797 patients with COVID- 19.
All studies reported on the prestige of smoking and, by comparison, patients with non-serious and serious diseases.The non-serious disease was explained as a benign “common type” disease that did not require attention in the ICU, while the serious disease was explained as critical, refractory, requiring ICU or fatal care.
Of the 10,797 patients included in the analysis, 9,414 (87.2%) were in a non-serious disease and 1,383 (12.8%) a serious illness.
Among non-severe cases, the prevalence of previous smoking is 5.2%, while in severe cases, the prevalence is 12.5%.
In addition, active smoking rates were 2.9% among non-severe cases and 5.9% among severe cases.
“As a result, a severe COVID-19 was observed nearly 1.5 to 2 times more in smoking history and existing smoking groups,” Gulsen and his team explain.
When the team analyzed existing smoking, in particular, the prevalence of serious illnesses was 10.7% among non-smokers, compared to 21.2% among active smokers.
Researchers say the findings that existing smoking is linked to a greater threat of severe COVID-19 have been reported previously.
“Our research adds to this developing consensus in the literature, presenting more studies and examining an existing smoking and smoking history with the threat of expanding the severity of COVID-19,” the team wrote.
Gulsen and his colleagues say that a recent meta-analysis indicated that severe headaches were observed in 48% of COVID-19 patients who were ex-smokers and in 24% of those who had recently smoked, which appears to be due to the fact that ex-smokers have been exposed to cigarette smoke for longer and then developed comorities such as COPD Explain.
Another recent meta-analysis showed that the progression of severe COVID-19 4.4 times more is not unusual in other people with COPD.
Researchers say there is growing evidence of the WHO warning that smokers are more likely to expand severe COVID-19 and possibly die later.
“SARS-VOC-2’s OUTBREAK inspires patients and those at risk to perform intelligent fitness practices and quit smoking,” they write.”In addition, doctors would possibly pay more attention to the smoking history of COVID-19 patients, and additional studies would possibly be intended to identify mechanisms that stimulate or decrease this threat.”
medRxiv publishes initial clinical reports that are not peer-reviewed and are therefore not considered conclusive, clinical practices/health-related behaviors, nor are they treated as established information.
Written by
Sally holds a bachelor’s degree in biomedical sciences (B.Sc.).He specializes in reviewing and synthesizing the latest discoveries in all covered medical spaces in major world-renowned, high-impact foreign medical journals, foreign press conferences, and newsletters from government agencies and regulators.At News-Medical, Sally generates news, articles about life sciences, and interview coverage.
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