Researchers evaluate the effect of coronavirus disease on others with progressive multiple sclerosis

Researchers conducting a giant foreign study on progressive multiple sclerosis (MS) tested the effect of the global coronavirus epidemic 2019 (COVID-19) on their study participants.

Compared to initial pre-COVID evaluations, the effects of COVID have an effect on the survey administered during lockdown that showed minimal adjustments in depression, anxiety and quality of life, as well as the effect of MS symptomatology on daily activities.

The article, “The Emotional Impact of the COVID-19 Pandemic on People with Progressive Multiple Sclerosis” (doi: 10.1007 / s00415-020-10160-7), published online on August 19, 2020 in the Journal of Neurology.SpringerLink COVID Collection: https://link.springer.com/article/10.1007/s00415-020-10160-7

The authors are members of the CogEx study team, made up of on-site researchers from Canada, the United States, Italy, the United Kingdom, Denmark and Belgium.COVID has an effect on research conducted during the suspension of a randomized clinical trial (ECA) involving 131 participants at 11 sites in the six countries mentioned above.The trial’s principal investigator is Anthony Feinstein, MD, PhD, university of Toronto.

The COVID pandemic has had a really extensive effect on the general population, which has led to considerations for populations at higher risk of infection, as well as the adverse mental and social effects of quarantine and social estating requirements.assess in real time the effect of the pandemic on the population with progressive MS.

Participants from all sites that responded to COVID have an effect on the survey, while the issue of social restrictions from May 2020 to July 2020.La COVID infection was reported in 4% of participants, according to lead writer Nancy Chiaravalloti, PhD, director of the Centers for Neuropsychology, Neuroscience and Traumatic Brain Injury at the Kessler Foundation.

Comparison of baseline with COVID tests revealed minimal adjustments in depression, anxiety and quality of life.The effect on MS symptomatology on the purposes of daily life was also minimal, unless in the small subset with COVID-19 infection, where having an effect on was significant.

“The minimal effects were what we expected to see,” Dr. Chiaravalloti said, saying the effects were consistent on other continents.

“People with progressive MS appear to have adapted better to blocking conditions.Knowing their greatest risk, they might have been the first to take protective measures, possibly provide a sense that they counteracted negative emotional reactions,” he speculated.”They are also used to living in medical uncertainty and social isolation, two main points that have fuelled the greatest degrees of mental discomfort in the general population.”

COVID has an effect on the survey showed that most participants actively participated in intellectual and physical activities during lockdown.

This is not unexpected given that the objective of the TCR is to measure the effects of these activities,” Dr. Chiaravalloti said.

Kessler Foundation

Chiaravalloti, N.D., et al.(2020) The emotional effect of the COVID-19 pandemic on others with progressive multiple sclerosis.neurologie.doi.org/10.1007/s00415-020-10160-7’s daily.

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