PORTLAND, Oregon (KGW) – Based on years of pre-pandemic studies, medicine and generation have complexes under the strain of COVID-19. Now, new studies from Oregon State University (OSU) may be a “universal” way to treat the virus, while also helping to fight other diseases.
“This is a transformative time,” said Gaurav Sahay, associate professor in OSU’s Department of Pharmaceutical Sciences. “Even though COVID has been a terrible time, what it has led to are those new technologies. “
According to OSU, Sahay and colleagues at OSU and the Texas Biomedical Research Institute demonstrated in a mouse-style that it is imaginable to provoke the production of a protein capable of preventing various variants of the SARS-CoV-2 virus from entering cells and causing respiratory illness. . .
The paintings of him are double.
First, they discovered a way to block various variants of COVID. It works by introducing so-called “decoy” enzymes into the framework that bind to coronavirus spike proteins and prevent the virus from attaching to healthy lung cells.
Second, they have reshaped the delivery of this nanotechnology.
“The delivery of this generation of mRNA is to encapsulate them in a packaging carrier called a lipid nanoparticle,” Sahaya said. “They’re usually administered intramuscularly. . . But they can be aerosolized so you can give them nasally or nebulized. “
Sahay said we would possibly be far from the remedy for human patients, although the effects of animal models are promising.
“Based on animal models, we have noticed that this protein begins to take shape after an injection in about two hours. It’s pretty fast,” Sahay said.