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According to Novavax’s GlobalData corporate profile, RSV vaccines were a key area of innovation known for patents. Novavax’s grant percentage in February 2024 was 52%. The percentage of subsidies is based on the ratio of the number of subsidies to the total number of patents. .
Coronavirus Spike Proteins for Stable and Immunogenic Vaccines
Source: United States Patent and Trademark Office (USPTO). Credit: Novavax Inc.
A recently granted patent (publication number: US11896664B2) reveals an unnatural spike glycoprotein of the SARS-CoV-2 virus with express modifications in its immunogenic properties. The modified CoV S glycoprotein comes with an inactivated furin cleavage site and mutations at amino acid express positions. The patent also covers a remote host motile containing this modified glycoprotein, in particular insect motilians such as Sf9 motiles, as well as a remote nucleic acid encoding the glycoprotein. In addition, the patent describes an immunogenic composition comprising the modified CoV S glycoprotein and a pharmaceutically appropriate buffer. The composition would possibly include express amounts of glycoprotein, a saponin adjuvant, and even a nanoparticle with a nonionic detergent core. Methods to stimulate an immune reaction against SARS-CoV-2 in a subject through the use of SARS-CoV-2 in SARS-CoV-2 are also detailed, adding dosing regimens and possible combinations with other immunogenic compositions. Overall, the patent aims to protect unique modifications of the SARS-CoV-2 spike glycoprotein and its programs in the progression of effective vaccines or remedies. opposite to the virus.
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GlobalData, the industry’s leading information provider, provided the underlying data, studies, and studies used to produce this article.
GlobalData Patent Analytics tracks bibliographic knowledge, knowledge about legal events, patent holders at any given time, and upstream and downstream citations from global patent offices. Textual research and official patent classifications are used to organize patents into key thematic spaces and link them to express companies.
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