Why more people reading the price of mouthwashes and nasals?
The apparent answer, of course, is that it is profitable. Salt water costs a few pennies; other products with antiviral activity charge only a few dollars. Why examine those non-unusual antiseptics when you can have new exotic drugs and lucrative vaccines?
Gilead’s reemployment, for example, costs more than $3,100 according to treatment, developed with $99 million in public funds. Similarly, the progressive vaccines provided costs ranging from $4 to the AstraZeneca-Oxford candidate, $13 for the Indian Serum Institute. , between $32 and $37 for the taxpayer-funded Modern vaccine, to $145 for SinoPharm.
But there are attractive indications that undeniable measures decrease viral load and can simply prevent transmission of SARS-CoV-2, the virus that causes Covid-19. These should be studied as a total as a total as a total as a total as a total.
The most comprehensive report, an in-depth review of mouthwash research, comes from the University Hospital of Wales in Cardiff. Professors Valerie O’Donnell and David Thomas that the SARS-CoV-2 virus (and other respiratory viruses) is surrounded by a fat membrane. This can break with soap or detergents, which is why washing your hands is so important. There are many non-unusual chemicals that also have this effect. We already use 70% ethanol (usually in hand sanitizers). Researchers sponsored by the assembly industry of the International Dental Research Association of 2010 have shown that an exposure of 30 seconds to 21. 6% ethanol with essential oils (Cool Mint Listerine, comprising eucalyptus, menthol, timol and methyl salicylate) leads to 99. 99% relief in a strain of H1N1 A influenza in tissue culture.
Chlorhexidine (Hibiclens et al. ) It has been used for a long time to cleanse the skin before surgery. It is also used in cancer patients for oral health and decrease the threat of infection with gum infections. Chlorhexidine has a giant antibacterial activity but has no intelligent antivirals activity and deserves not to be used for coronavirus.
Iodine has also been used to whiten skin sores for decades. It has been used as gargantism in Japan and India for sore throats due to its antiviral activity.
Contact with hydrogen peroxide, at a concentration of 0. 5%, will inactivate fat-coated viruses such as coronavirus.
Cetylpyridium chloride (CPC), a type of antiseptic, also has antiviral effects and has been used in mouthwashes and throat pills.
A small randomized controlled nasal irrigation and gargles with salt water showed a shorter disease, 35% relief in infection of other family members and relief in viral excretion.
Finally, even gargling with chlorinated tap water reduced respiratory infections in Japan.
Another small test from Malaysia showed greater relief from the virus with iodine or oils compared to water or lack of treatment.
A recent study in Germany found that Listerine, Iso-Betadine and Dequonal mouthwashes are of maximum efficacy compared to 3 strains of SARS-CoV-2 out of every 8 commercially available products.
There are many questions about this approach. Can you reduce the viral load enough through gargles and/or nasal washes (p. E. g. Pot Neti) to be a valid preventive measure?Which product is of maximum efficiency?Would a mixture be better?How much contact time is required?Would it be more effective to put these compounds on a gum or pill to prolong contact?What are the effects of these antiseptics on oral flora (microbiome)?Do we want nasal rinses, mouthwashes or both?
What side effects do they appear? (We already know teeth spots and rare allergic reactions).
There is a report in the CURE ID Drug Reuse database of an unpublished case in which excessive use of iodine in the mouth and nasal spray has resulted in higher levels of iodine and mild bleeding. The challenge was solved by preventing aspirin and reducing iodine use. it is an example of the price of CURE ID and the desire to ensure that more fitness personnel present cases, which is simple to do (the database and discussion forum are an assignment from the FDA and NCATS of NIH. for fitness staff).
El Dr. O’Donnell emphasizes the need to press clinical trials to achieve effectiveness against SARS-CoV-2: “The use of mouthwash, such as gargling, has not so far been considered through public fitness agencies in the UK or elsewhere. “Seems. She noted: “Now there’s a little bit of interest nowArray . . . [there are] several studies comparing the oral addressing of the virus now in the world.
Studies are being planned through UCSF and Karachi University, where reasonable products are found.
Given the magnitude of the Covid-19 pandemic, it would seem moderate to recommend that others start with one of those mouthwashes or gargles and nasal irrigation as soon as respiratory symptoms appear, to perhaps decrease their contagion. yourself too.
[Message updated on 30/08/20]
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I am a specialist in infectious diseases and Resilience: the story of hope and triumph over the evil of a family and the conduct of clinical research, the essential guide
I am a specialist in infectious diseases and Resilience: the story of hope and triumph over the evil of a family and the conduct of clinical research, the essential consultant of the subject.