The number of other people who can attend social gatherings will drop to six in England following a backlog of coronavirus cases across the UK. NO
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Covid-19 vaccine progression trials through AstraZeneca and the University of Oxford were suspended due to a reported side effect in a patient in the UK. N n
AstraZeneca posted Tuesday night saying that studies on the latest stage of the vaccine have been suspended while the company examines whether the reported appearance effect through the patient is similar to the vaccine.
AstraZeneca did not disclose any data on the patient’s condition other than describing it as “a potentially unexplained illness. ” News site Stat first reported on the verification disruption, saying that the imaginable look effect had occurred on a verification volunteer in Britain, who needed to recover.
The vaccine, developed through the University of Oxford, is being tested in thousands of people in Britain and the United States, and in smaller test teams in Brazil and South America.
An AstraZeneca spokeswoman said the rupture is part of a popular screening procedure that leads to a judgment if there is a reported “potentially unexplained illness” in a control subject, and that the subject’s illness may also be a coincidence.
“In the ongoing global randomized controlled trials of the Oxford coronavirus vaccine, our popular review procedure was activated and we voluntarily discontinued vaccination to allow review of protection knowledge by an independent committee. The spokesperson said in a statement.
“This is a regimen action that occurs whenever there is potentially unexplained illness in any of the trials, while it is under investigation, making sure that we maintain the integrity of the tests.
“In the giant trials, the diseases are due to chance, but they have to be analyzed independently to check this carefully.
“We are racing to expedite the review of the single occasion to minimize any possible effect on the trial schedule. We are committed to ensuring the protection of our participants and the highest standards of conduct during our rehearsals. “
No main points were given about the patient suffering from the effect of the prospective aspect or the nature of the reaction. Temporary suspensions from primary medical studies are not uncommon, and for unforeseen reactions it is a mandatory component of protective testing.
The duration of the break from AstraZeneca not without clear delay. Two other vaccines are undergoing large, late-stage trials in the United States, one made through Moderna Inc and the other through Pfizer and the German company BioNTech. Statistics reported a total of nine candidate vaccines in late phase or phase 3 trials, with AstraZeneca being the first trial known to have been suspended.
Despite some figures, such as that of the President of the United States, Donald Trump, who insists that a vaccine will be available in a few months, the University of Oxford says that a vaccine may not be available until 2022.
The university is under pressure that clinical trials deserve the utmost care. “It takes time to expand and apply effective vaccines, generally five to ten years on average.
Despite promising reports of potential progressing coronavirus vaccines around the world, it may still take 12 to 18 months to expand one, ”says a university document dated August 25. Array “It is imperative that clinical trials be conducted with the utmost care to ensure the protection of participants and to fully identify the protection profile of new products.
“Security is largely monitored during verification through the national regulator with a requirement for a protection report to be placed on investigators, verification and inspections of verification processes and procedures through the regulator,” and a committee independent protection watchdog that actively reviews protection during conduct. of the clinical trial.
“When an application for use of the vaccine is submitted to a regulatory body, they will fully assess the protection and efficacy knowledge of the trials and use them to inform their resolution related to prospective use. “
There are significant delays on the M1 at Leeds this morning after a twist of fate that left debris strewn across the road.
The M1 southbound from the J46 towards Austhorpe to the J45 East Leeds is completely closed due to a turn of fate involving a capsized car.
Police and traffic officers on site to investigate.
Traffic is diverted onto J46 and allowed to register on the dual carriageway on the southbound access form at the same junction, police said.
Due to ongoing investigations, this closure between the straps is expected to remain in place for the next several hours, Tuesday’s rush hour.
More soon.
The number of new coronavirus cases in one day was recorded in Leeds.
On September 2, a total of new cases were recorded according to Public Health England.
This is the largest daily accumulation in more than 4 months.
The most recent knowledge of last week, in format DATE CASES CUMULATIVE CASES is the following:
04-09-2020, 29, 4. 841
03-09-2020, 5, 812
02-09-2020, 74, 4. 758
01-09-2020, 61, 4. 684
31-08-2020, 35, 4. 623
30-08-2020, 28, 4,588
08-29-2020, 35, 4,560
28-08-2020, 43, 4. 525
27-08-2020, 46, 4. 482
It is available to the public by clicking here.
Seven £ 10,000 fines have been imposed on illegal rave organizers in Leeds, the town council leader said. N n
Judith Blake said she had “fully expected” the city to be included on the government’s coronavirus watch list after a recent backlog of cases.
And he suggested that young people “recognize their own responsibility” in controlling the spread of the virus after reports of an increase in space parties in the city.
Ms Blake told BBC Breakfast on Saturday: ‘We are tracking our numbers every day and we recognize that the numbers have increased, so we expected our list to be a concern. ‘
“We think there is a bit of complacency ahead. What we are seeing is that the numbers are changing and, in fact, more and more young people test positive and are spreading throughout the city.
“So as we focused more on express communities in the beginning, it is now clear that the trend is changing. “
Leeds, with South Tyneside, Corby, Middlesbrough and Kettering, have been included on the government’s “areas of concern” watch list following a spike in Covid-19 cases.
Ms. Blake said the council was working heavily with the city’s universities before the academics returned, adding that additional testing is being considered.
She said the council also urged young people to “acknowledge their own responsibility” to help reduce the spread of the virus.
“Unfortunately, we have noticed an increase in space parties, but we are running with the police,” Blake said.
“Last weekend we, with the police, imposed seven of the £ 10,000 fines imposed on organizers of illegal raves. “
The fines are from a new law that are intended to deter illegal music events.
While organizers can be fined £ 10,000, other non-masked people and participants in illegal gatherings can be fined £ 100, doubling for repeat offenses to a maximum of £ 3,200.
A disabled Leeds activist who suffers from chronic pain campaigns against primary adjustments in patients as they are treated.
A woman who took her car for a roadworthiness test says the son of an unlicensed mechanic took her for a drive and ran her over in opposition to the motorist, who later sued her for a claim. NO
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AstraZeneca issued a statement on Tuesday night saying the late-stage studies of the vaccine had been paused while the company investigates whether the patient’s reported side effect is connected with the vaccine.
AstraZeneca did not reveal any information about the patient’s condition other than to describe it as “a potentially unexplained illness”. News site Stat first reported the pause in testing and said the possible side effect occurred in a testing volunteer in Britain, who was expected to recover.
The vaccine, developed by Oxford University, is being tested in thousands of people in Britain and the US, and in smaller study groups in Brazil and South America.
An AstraZeneca spokeswoman said the pause was part of a standard review process which occurs in trial if there is a “potentially unexplained illness” reported in any trial subject, and that the subject’s illness could also be coincidental.
“As part of the ongoing randomised, controlled global trials of the Oxford coronavirus vaccine, our standard review process was triggered and we voluntarily paused vaccination to allow review of safety data by an independent committee,” the spokeswoman said in a statement.
“This is a routine action which has to happen whenever there is a potentially unexplained illness in one of the trials, while it is investigated, ensuring we maintain the integrity of the trials.
“In large trials illnesses will happen by chance but must be independently reviewed to check this carefully.
“We are racing to expedite the review of the single occasion to minimize any possible effect on the trial schedule. We are committed to ensuring the protection of our participants and the highest standards of conduct during our rehearsals. “
No details about the patient suffering the potential side effect, or the nature of the reaction, were given. Temporary holds of large medical studies are not uncommon, and looking into any unexpected reactions is a mandatory part of safety testing.
The duration of the break from AstraZeneca not without clear delay. Two other vaccines are undergoing large, late-stage trials in the United States, one made through Moderna Inc and the other through Pfizer and the German company BioNTech. Statistics reported a total of nine candidate vaccines in late phase or phase 3 trials, with AstraZeneca being the first trial known to have been suspended.
Despite some figures, such as US President Donald Trump, insisting a vaccine will be ready in a matter of months, Oxford University says a vaccine might not be ready before 2022.
The university stressed clinical trials had to be conducted with the utmost care. “It takes time to develop safe and effective vaccines – usually five to ten years on average.
Despite promising reports about potential coronavirus vaccines being developed worldwide, it could still take an estimated 12-18 months to develop one,” a document on the university’s website, dated August 25, reads. “It is essential that clinical trials are conducted with great care to ensure the safety of the participants and to fully establish the safety profile of the new products.
“Safety is overseen closely during the trials both by the national regulator with a requirement of safety reporting placed on investigators throughout the trial, and inspections of the trial processes and procedures by the regulator, and an independent safety monitoring committee who reviews safety actively during the conduct of the clinical trial.
“When an application for use of the vaccine is made to a regulator, they will fully assess the safety and efficacy data from the trials and use that to inform on their decision about potential use.”
There are major delays on the M1 in Leeds this morning after a crash left debris strewn across the carriageway.
The M1 southbound from J46 for Austhorpe to J45 East Leeds is fully closed due to a crash involving an overturned car.
Police and traffic officers remain on the scene investigating.
Traffic is being diverted off at J46 and is allowed to rejoin the motorway on the southbound entry slip at the same junction, police said.
Due to ongoing investigations this closure between the slip roads is likely to remain in place for the next few hours – during rush hour on Tuesday.
More to follow.
The highest number of new coronavirus cases in one day has been recorded in Leeds.
On September 2, a total of 74 new cases were recorded according to Public Health England.
This is the highest daily increase in more than four months.
The latest data for the last week – in the format DATE CASES CUMULATIVE CASES is as follows:
04-09-2020, 29, 4,841
03-09-2020, 54, 4,812
02-09-2020, 74, 4,758
01-09-2020, 61, 4,684
31-08-2020, 35, 4,623
30-08-2020, 28, 4,588
29-08-2020, 35, 4,560
28-08-2020, 43, 4,525
27-08-2020, 46, 4,482
The information is available to the public by clicking here.
Judith Blake said she had “fully expected” the city to be placed on the Government’s coronavirus watchlist following a recent rise in cases.
And she urged young people to “recognise their own responsibility” in controlling the spread of the virus following reports of an increase in house parties in the city.
Ms Blake told BBC Breakfast on Saturday: “We have been monitoring our number every single day and we recognise that the numbers have been creeping up, so we fully expected to be on the list to become an area of concern.
“We feel there is a bit of a complacency coming in. What we are seeing is the numbers are changing, and actually more young people are testing positive and they are spread around the city.
“So whereas we were focusing more on specific communities at the beginning, it is now clear the pattern is changing.”
Leeds, along with South Tyneside, Corby, Middlesbrough and Kettering, have been placed on the Government’s “areas of concern” watchlist following a spike in Covid-19 cases.
Ms Blake said the council was working closely with the city’s universities ahead of students returning, adding that additional testing was being considered.
She said the council was also urging young people to “recognise their own responsibility” in helping to reduce the spread of the virus.
“Unfortunately we have seen a rise in house parties, but we are working with police,” Ms Blake said.
“Last weekend we issued, with the police, seven of the £10,000 fines for organisers of illegal raves.”
The fines are part of newly introduced legislation aimed at deterring illegal music events.
While organisers can be hit with £10,000 fines, people not wearing masks and participants in unlawful gatherings can be fined starting at £100, doubling for each repeat offence up to a maximum of £3,200.
A disabled activist from Leeds who suffers from a chronic pain condition is campaigning against major changes to the way patients like them are treated.