Japanese researchers conducted a study in which they learned an effective remedy for patients who are severely positive in Covid-19 suffering from inflammatory responses.
The study published in the journal PNAS. Researchers tested the symptoms of the virus that persist even after the patient has recovered from an active viral infection.
Researchers observed in their study that cytokines are an organization of small proteins that can inhibit or inhibit the human body’s immune reaction to infections, traumas and diseases such as cancer.
One of its functions is to stimulate inflammation, which initiates the healing process.
The challenge is that overstimulation of the inflammatory reaction has a variety of destructive complications, ranging from asthma to severe autoimmune diseases, the team noted in his study.
Researchers also argued that such a complication, called cytokine syndrome (CRS), has been observed in patients with a hyperimmune reaction to a microbial infection or trauma, which can lead to organ failure and even death.
The lead author of the study, Sujin Kang, of Osaka University in Japan, said in a statement: “While you know what cytokines are involved, there is still no express immunotherapy for CRS and the remedy is limited to supportive care. “
“To improve the molecular mechanisms of CRS pathogenesis, we first studied the cytokine profiles of 91 patients diagnosed with CRS related to bacterial sepsis, acute respiratory misery syndrome or burns,” Kang added.
The team said the highest grades of pro-inflammatory cytokines were also related to more severe cases of pneumonia, a non-unusual cause of death in Covid-19 patients.
Researchers used an antibody-based drug called Actemra for patients with severe Covid-19. The drug contributes to the immediate decrease in the degrees of pro-inflammatory cytokines and can simply relieve severe symptoms of the disease.
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