Influenza outbreaks would possibly be similar to those of COVID-19; drugs get advantages from arthritis seen

The following is a summary of some of the most recent clinical studies on the new coronavirus and efforts to remedy and vaccines that oppose COVID-19, the disease caused by the virus.

Influenza may be related to the spread of coronavirus

Influenza epidemics would possibly be related to the spread of COVID-19 infections, according to a European study that has created a mathematical style of transmission of the new coronavirus in Belgium, Italy, Norway and Spain and estimates that the highest rates of influenza infections would be linked to increased coronavirus transmission in the country, Matthieu Domenech de Celles , from the Max Planck Institute for Infection Biology in Berlin, who said estimates, published Wednesday on the medRxiv online medical page prior to peer review, were consistent with past research.

In Italy, he noted, the highest rates of influenza vaccination were linked to lower death rates from COVID-19. In addition, he said, a US review of the US and its allies in the Middle East has been a But it’s not the first time Of nearly 11,700 others screened for COVID-19, he found that those with flu shots were less likely to test positive.

None of these studies show that influenza vaccinates the spread or threat of an individual to COVID-19, and other points would possibly explain associations. However, he said M. de Celles, before “the next ‘twindemic'” of seasonal influenza and COVID In the northern hemisphere, “our effects recommend the desire to increase influenza vaccination”, which can also not only reduce the burden, but also restrict cases of COVID-19.

Rheumatoid arthritis drug is helping to cure COVID-19

Hospitalized patients of COVID-19 treated with remdesivir, an antiviral drug from Gilead Sciences Inc. , recovered approximately one day earlier, on average, if they won baricitinib, Eli Lilly and Co. ‘s rheumatoid arthritis drug, found clinical trial researchers.

The trial, sponsored through the U. S. National Institute of Allergy and Infectious Diseases (NIAID). Included more than 1,000 patients. The test also showed that for patients who did not get the arthritis medication, those who earned it performed more than 15 days after enrolling. at trial.

According to the data, Lilly plans to discuss possible emergency use authorization with the U. S. Food and Drug Administration. The corporation announced the effects of the so-called ACTT-2 essay in a press release on Monday. The effects have not yet been officially published.

Experts tell when to use COVID-19 antibodies

COVID-19 antibody tests, known as serological tests, are widely available, but evidence of their usefulness is limited, the Society of Infectious Diseases of America said in revealing new rules published Saturday in the journal Clinical Infectious Diseases.

Antibodies opposed to the new coronavirus do not appear in the blood for some time after a user has been infected, so serological tests are unreliable to diagnose COVID-19 unless the patient has been for weeks, according to guidelines.

The authors panel, headed by Dr. Kimberly Hanson of the University of Utah, met 3 cases in which an antibody opposed to coronavirus would be justified: the first is when doctors strongly suspect that a patient has COVID-19, but that molecular diagnosis s with reference PCR looking for genetic parts of the virus have been negative and it has been at least two weeks since the onset of symptoms The time is when a child presents symptoms and symptoms of multisistmic inflammatory syndrome, a life-threatening disease that has the third is when public aptitude officials conduct so-called seromonitoring studies to track the proportion of the population that has been exposed to the virus.

Newly discovered coronavirus proteins could possibly be immune triggers

Scientists have discovered 23 unknown proteins produced through the new coronavirus in the past, 4 of which can simply activate patients’ immune system to act or, in some cases, overreact and cause serious illness.

For the most part, the proteins of this new virus have been known based on PC predictions and similarities with other coronaviruses, but those researchers have taken a different approach. Following protein-producing “machines” in cells called ribosomes, they had to accurately map which parts of the virus’s genetic code were translated into proteins, as co-leader Yaara Finkel of the Weizmann Institute of Science in Israel told Reuters.

Most newly discovered proteins probably have regulatory purposes in the virus, i. e. they help keep it active, with the exception of the 4 “full proteins” that can alert the immune formula to the presence of a foreign invader, Ms. Finkel and her colleagues wrote in a study published Wednesday in the journal Nature. More paints are needed on the role these proteins play in infection, Finkel said, though this wisdom may simply “lead to a greater understanding of the progression of infection, as well as better tactics to treat COVID-19 or avoid a harmful immune overrehension. “Reuters

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