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Many medical experts expect us to revel in a complicated winter because of what fitness officials call a dual epidemic: a backlog of COVID and flu cases hitting at once. “We expect the unexpected,” epidemiologist Michael Osterholm, PhD, MPH, founder and director of the Center for Infectious Disease Research and Policy at the University of Minnesota said in an interview with the Journal of the American Medical Association.
In addition to a brutal flu season, COVID cases are expected to rise this winter as new variants emerge in Europe and the United States. of the disease this winter in the United States, as this is already beginning to occur in Europe and the United Kingdom,” said Gregory Poland, a virologist and vaccine researcher at the Mayo Clinic. The media also states: “BQ. 1 and BQ. 1. 1, very similar, accounted for 16. 6% of coronavirus variants in the country, almost double that of last week, while Europe expects them to be the dominant variants in a month. The European Centre for Disease Prevention and Control said variants are likely to be developed in the coming weeks or months in the European region. Both variants are descendants of the BA. 5 subvariant of Omicron, which is the dominant form of the coronavirus in the region. U. S. regulators in Europe and the U. S. They have recently legal vaccine boosters targeting him. “
Keeping your immunity strong this season is imperative to fight the flu and COVID. And while COVID protective precautions have been lifted, experts still propose social distancing, wearing a mask, and making sure you’re not deficient in nutrients like B, C, and D. Health officials are also urging others to continue getting most flu and COVID vaccines and boosters. According to experts, eat this, not that! Health spoke with, here’s what you want to know about Pfizer’s recall. As always, consult your doctor for medical advice. Read on and to make sure you are physically fit and the fitness of others, don’t miss those certain symptoms you have. I already had COVID.
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Gladstone Institutes principal investigator Nadia Roan PhD told 6 ABC WPVI-TV Philadelphia, Pennsylvania: “XBB spread very temporarily to Singapore, where it surpassed BA5. . . Or they are wonderful scary because they are highly transmissible. ” The news outlet also reports, “The CDC already attributes 5. 7% of cases in the United States to the BQ. 1 variant and forty-seven sequences to XBB to the knowledge of a foreign studies organization that tracks those strains. Dr Roan adds: “They mutated their surface proteins in such a way that the antibodies, requested either through past infection or through vaccination, are not necessarily opposed to them. That’s why they’re so highly transmissible. “
Eli E. Hendel, MD, a three-time board-certified pulmonologist, sleep medicine specialist and internist, medicine leader at Dignity Health Glendale Memorial Hospital and his own user practice tells us, “We’ve had variations, it’s not new The average inflamed user sees over a billion replicated copies. Of course, not all of them will be the best replications and there will be many faulty variants that will not survive. There were several that had an exclusive composition, the most lethal was Delta. . was, however, a more common detail in all previous variants. This is called “antigenic distance” and Omicron, by adding the existing BA 5, is very different. This antigenic distance refers to the protein series of the spike.
This would recommend that previous herd immunity would be useless for this variant. Some knowledge recommends this. This year, knowledge of two countries. Portugal, the country with the highest vaccination rate and South Africa, the country with the highest proportion of inflamed population, which had antibodies. Both countries have noted an increase in hospitalization rates this year compared to the omicron variant. The hospitalization rate increased until April of this year, after which there was a decrease. “
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Dr. Hendel explains, “To take a look at this question, you want to perceive the human immune system. There are two types, innate immunity and the immune cells we are born with. It is composed of primitive cells. They differ when faced with an antigen. When those immune cells differentiate, they shape adaptive immunity. They are highly specialized antigens. They have memory B cells, helper and killer T cells, and B cells that produce antibodies.
Adaptive immunity is explained and does not have much flexibility. Innate immunity can be mobilized to whatever is presented. In this sense, innate immunity can identify and respond to any variant of COVID. Studies have shown that interferon, a mediator of innate immunity activity, is superior in other people with mild disease and low in other people with severe disease. This implies that innate immunity plays a role in mitigating infection. “
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Dr. Hendel shares, “Innate immunity weakens with age and adaptability is strengthened. A strong defense desires any kind of immunity. Think of it as a strong army that has normal forces (adaptive immunity) and a reserve army (innate).
When the enemy attacks, you face the active specialized forces: airborne department (B cells that extract antibodies), amphibians (DC4 auxiliary cells), ground forces (CD8 killer cells) all guided through the intelligence accumulated through the enemy (memory cells B) Having had the vaccine against the spike protein will allow you to create missiles with steering formula (neutralizing antibodies of the spike protein) instead of a bombardment Disorganized Quasam rockets aimed at civilian spaces that cause many civilian casualties without achieving an army target (it is the typhoon cytokine that occurs in hospitalized patients in intensive care that is to blame for the increased mortality).
The explanation for why the worst end results are for unvaccinated patients is that the immune formula is off guard and immune cells will have to temporarily differentiate and create inflammatory mediators called cytokines. This causes severe respiratory failure, blood clots, sepsis. that’s why the most effective drug was not antivirals (Remdesevir) but steroids (dexamethasone). “
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Prolonged COVID remains a fear, and according to the Centers for Disease Control and Prevention, “nearly one in five American adults who have had COVID-19 still have ‘prolonged COVID. ‘
Tameem Alhayya MD, head of the Department of Medicine and Family Medicine at Beverly Hospital and co-founder and CEO of Sunrise Medical Associates, LLC, says, “Long COVID” is when patients continue to revel in symptoms beyond four weeks that cannot be explained through a diagnosis of choice. Patients regularly complain of fatigue, dyspnea, chest pain and cough. More rarely, insomnia, arthralgia (joint pain) and headaches. Patients may also experience mental or cognitive disorders such as PTSD, anxiety, depression, and poor memory and concentration. The prolonged COVID remedy is basically supportive with rehabilitation and symptomatic to relieve symptoms. I would argue that the most effective remedy for prolonged COVID is to avoid the disease itself by following CDC rules for vaccines and boosters. “
Dr. Suman Radhakrishna, director of infectious diseases at Dignity Health California Hospital, tells us, “Prolonged COVID symptoms are not unusual in other people with severe COVID infection. Patients with mild symptoms may also suffer from prolonged COVID. Persistent fatigue, headaches, impaired intellectual fitness and cognition, palpitations, and shortness of breath are some of the most common symptoms that are not reported in unusual ways. Most over time. We are still trying to perceive this problem. Patients found help to treat symptoms and allow time for the recovery process. “
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Gabrielle Einstein Morrow MD, medical director of the Emergency Department at Dignity Health Glendale Memorial Hospital and TeamHealth, says, “Most experts wait two months after their last Pfizer vaccine to receive the new booster. Those who recently had COVID would have to wait two months to receive the booster, but you can wait up to 3 months. “
Dr. Hendel says, “It’s been at least 6 months since the last recall. It’s for everyone. Remember that the maximum effective antibody is the one that targets the site of the spike protein that binds to the host mobile to penetrate. It is called receptor binding domain (RBD); These are called “neutralizing antibodies. “There are no lab tests to measure them yet, so it doesn’t make much sense to measure serum antibodies in other people at this time. Antibodies are just the rest of the motives involved in war (like the analogy with the army I explained earlier). “
Dr. Alhayya states, “The CDC’s most recent recommendations are that for all Americans over the age of five who have completed a number one series of a Pfizer-BioNTech COVID-19 vaccine (including those who have already received more booster doses with a monovalent vaccine) get a booster dose with one of the bivalent mRNA vaccines (Original and Omicron BA. 4/BA. five) at least two months after the Last dose of the vaccine. Booster doses are not yet allowed for children under five. “
Michael D. Wang, geriatric medicine, medical staff at Beverly Hospital, vice president of clinical affairs at Welcome Health Medical Group, a number one senior care and home care organization, says, “It’s glorious when I hear about someone who’s won the vaccines, whether it’s Pfizer, Moderna or whatever. That’s one of the main reasons we don’t see the terrible increases in endemic cases and hospitalizations that we had in the beginning. But the preparation of our immune formula slips over time and they have new coronavirus variants. Now, you can get boosters that are effective in harnessing our immune formula to get back to being ready, instead of falling asleep. And to protect your life and the lives of others, don’t stop at any of those 35 puts where you are maximum probably to catch COVID.