Groove may not be the only thing in the center when you have a Covid-19 coronavirus infection. Two newly published studies in JAMA Cardiology have discovered evidence that Covid-19 coronavirus can succeed at its center. And not in a smart kind of romantic comedy or BTS.
Both studies came here from Germany. One of a series of autopsies performed on 39 other people who died after having Covid-19. Thirty-five of those patients had died of pneumonia. A team from the University Heart and Vascular Center in Hamburg, Germany, (Diana Lindner, PhD, Hanna Bruninger, MS, Katharina Scherschel, PhD, Paulus Kirchhof, MD, Stefan Blankenberg, MD, Dirk Westermann, MD), University Medical Center Hamburg -Eppendorf (Antonia Fitzek, MD, Caroline Edler, MD, Kira Meissner and Klaus Peschel, MD) and the Institute of Cardiac Diagnostics and Therapy in Berlin, Germany, (Ganna Aleshcheva, PhD, Felicitas MD and Heinz – Peter Schultheis , MD) reported on the results.
Most (61.5%) of these autopsies revealed evidence of Severe Acute Respiratory Syndrome (SARS-CoV2) Coronavirus 2 at the center. Of those 24 cases, 16 had more than 1000 copies compatible with viral RNA micrograms, suggesting that there were giant amounts of viruses. In fact, in all five cases with the highest viral load, even when the center wasn’t working, the virus was. These viruses were still replicating, meaning they were still playing or were necessarily the viral edition of the villain.
The other examination was conducted through a team at the University Hospital Frankfurt in Frankfurt-on-Main, Germany (Valentina O.Puntmann, MD, PhD, M. Ludovica Carerj, MD, Imke Wieters, MD, Masia Fahim, Christophe Arendt, MD, Jedrzej Hoffmann, MD, Anastasia Shchendrygina, MD, PhD, Mariuca Vasa-Nicotera, MD, Andreas M. Zeiher, MD, Maria Vehreschild, MD and Eike Nagel, MD) They followed a hundred patients in the state of Hesse (which rhymes with “developed mendacity downwards”) who in the past had tested positive for SARS-CoV2.
For the study, these patients underwent an MRI from their center and blood tests for symptoms of damage at the center. This did not happen without delay after his covid-19 coronavirus diagnoses, but a median of 71 days later, more than two months after the initial diagnosis. They were also other people who still had a young mindset, literally, the average age was 49. Many of them were also not very ill, with two-thirds of the patients not even hospitalized.
However, MRIs showed that 78% of patients had an abnormality at their center. These ranged from inflammation symptoms to an enlarged left ventricle to minimize its center’s ability to pump blood to the rest of the body. Many of these effects were compatible with patients with myocarditis or pericarditis.
What is myocarditis? Well, myocardium is not the opposite of your o-cardium, but rather another way of saying central muscle. Adding “-itis” to the end of the myocardium means that the central muscles are inflamed. It’s not smart to inflame the core muscles. (In fact, anything that is inflamed is intended not to be smart.) Inflammation can cause damage. When the core muscles break, they can’t pump so well. This can lead to severe myocarditis and a failure of the center. This can also lead to a central attack or stroke, because when your center doesn’t pump well, blood can build up at its center and form clots. These clots can then move to your coronary arteries or arteries that supply blood to your brain. A weakened central muscle can also cause abnormal central rhythms, as broken muscles may not conduct electricity well. One of the imaginable consequences of abnormal central rhythms, when in fact abnormal, is sudden cardiac death. And as you can imagine, death is not a smart outcome.
What is pericarditis? It’s not two little girls, but an inflammation of the pericardium, the membrane sac that surrounds your center. It’s essentially a bag around your center. Inflammation of this pouch can also interfere with the rhythm and function of your center.
Myoperocarditis occurs when you have pericarditis and myocarditis. It’s not a two-for-one deal.
Twelve of the patients on the test had evidence that portions of their core muscles were not getting enough oxygen. Three patients had abnormalities so severe that they had to undergo central tissue biopsies to see more closely what was happening. Samples from her central tissue revealed active inflammation but no symptoms of the virus.
It’s not everybody. Most (76%) patients had detectable troponin in their blood. Seeing troponin in the blood is like seeing ping-pong balls on the ground when they’re meant to be in a lottery ball machine. This means that anything must have happened to the lottery ball machine. Similarly, troponin is a protein commonly found in the core muscles. When your central muscle is damaged, troponin may leak into your bloodstream. In addition, on the day of MRI, 17 patients still suffered from chest pain, 20 central palpitations and 36 persistent dyspnoea and general exhaustion.
According to this review alone, the cause of all these findings is not entirely clear. Remember that it was more than two months after the diagnosis of Covid-19. Were those patients still inflamed by the virus? Was there still a challenge with the immune reaction to the virus? Was this residual damage due to an infection? Were the blood clots the culprits? After all, as William A. Haseltine has already covered for Forbes, studies have shown that Covid-19 coronavirus infection can lead to the formation of blood clots. How permanent is the pain? What’s that pain like? Note that the samples from these studies were relatively small and not random. So do the numbers really apply to everyone who gets Covid-19? As with Donnie Darko’s film, there are still many questions left.
Covid-19 coronavirus would not in fact be the first virus to cause myocarditis or pericarditis. Various viruses can cause situations such as adenovirus, hepatitis B and C viruses, parvovirus, Epstein Barr virus and herpes simplex virus. It is increasingly transparent that the Covid-19 coronavirus is like this more productive type that talks about the groom’s relationships beyond his wedding toast. It does not respect the limits and can travel far beyond your respiratory system.
These two studies in JAMA Cardiology, as well as the study of a case of an otherwise healthy and nearby 53-year-old acute myopriocarditis published in a March JAMA Cardiology factor, raise the option that Covid-19 coronavirus possibly cause severe central tears, not the way NSYNC perceives it. Could the infection eventually lead to cardiomyopathy (central muscle problems) and failure of the center? Maybe. Maybe. Well, it probably would be. More studies are needed to perceive what this mysterious SARS-CoV2 may also end up doing to you.
I am a writer, journalist, teacher, system modeler, expert in PC and virtual fitness, bar eater and entrepreneur, not in that order. I’m right there.
I am a writer, journalist, teacher, system modeler, expert in pc and virtual fitness, eat lawyers and entrepreneur, not at all times in that order. Currently, I am Professor of Health Policy and Management at the City University of New York School of Public Health (CUNY), Executive Director of PHICOR (@PHICORteam), Professor courtesy at Johns Hopkins Carey Business School and Founder and CEO of Symsilico. The above positions come with Executive Director of the Global Center for Obesity Prevention (GOPC) at Johns Hopkins University, Associate Professor of International Health at Johns Hopkins’ Bloomberg School of Public Health, Associate Professor of Biomedical Medicine and Informatics at the University of Pittsburgh, and Senior Manager of Quintiles Transnational, Biotech Equity Research at Securities and co-founder of a biotechnology/bioinformatics company. My paintings have come with upcoming approaches, models and PC equipment to help fitness and fitness decision makers on each and every continent (except Antarctica) and have received the support of a wide variety of sponsors such as the Bill and Melinda Gates Foundation, NIH. , AHRQ, CDC, UNICEF, USAID and Global Fund. I have written more than two hundred clinical publications and 3 books. Follow me on Twitter (@bruce_y_lee) but don’t ask me if I know martial arts.