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According to new research from adults hospitalized with COVID-19 in Los Angeles between December 2021 and April 2022, peak blood pressure more than doubled a person’s risk of hospitalization due to an Omicron variant COVID-19 infection, even in the presence of a full vaccination by adding a booster dose of COVID-19 vaccines.
Even in the absence of other chronic diseases such as type 2 diabetes, kidney disease, or heart failure, high blood pressure, known as hypertension, has continued to affect severe COVID-19 disease.
According to the study’s senior author, Joseph E. Ebinger, M. D. , M. S. , an assistant professor of cardiology and director of clinical research at the Smidt Heart Institute at Cedars-Sinai Medical Center in Los Angeles, “These findings are due to the fact that a portion of adults in the United States have hypertension. “
At the beginning of the pandemic, COVID-19 vaccines helped reduce mortality and some of the worst secondary symptoms of infection. An observational study in Israel found that a booster dose of the COVID-19 vaccine further reduced the risk of serious illness through up to 70%. However, some other people who had received the full dose and booster dose still had to be hospitalized for COVID-19, the first outbreak of the omicron variant.
The Omicron version, which remains the primary type, was first discovered in the United States in December 2021, according to the U. S. Centers for Disease Control and Prevention. UU. Se discovered seven subvariants of Omicron in July 2022.
Although the research organization included participants who had won the entire series of COVID-19 vaccines and a booster dose, Ebinger and his colleagues sought to examine the characteristics of other people who had COVID-19 cases severe enough to require hospital care.
The knowledge revealed that other older adults without other underlying medical situations are also at risk, according to Ebinger. Even if a user does not have other vital chronic diseases, an advance of Omicron infection severe enough to require hospitalization can have effects on an adult of any age, especially if that user has high blood pressure. These are not the ones we assume have the maximum risk. The discovery that they are not the ones in poor health was unexpected.
During an Omicron surge between December 2021 and April 2022, in the greater Los Angeles area, 912 adults who had gained at least 3 doses of a COVID-19 mRNA vaccine (either the Pfizer-BioNTech vaccine or Moderna COVID-19, legal through the U. S. Food and Drug Administration). USA) and were treated for COVID-19 were the subject of a retrospective cohort study. Age, gender, race, ethnicity, and clinical knowledge of electronic fitness records were among the top demographic points examined. Lifestyles of chronic medical diseases such as type 2 diabetes, kidney disease, attacks on the center, center failure, and beyond chronic obstructive pulmonary disease or asthma are examples of critical clinical features and variables that researchers have discovered.
According to the data, about 16% of the other 912 people who received all three doses of the COVID-19 mRNA vaccine required hospitalization.
* The risk of hospitalization was found to be higher due to complex age, high blood pressure, chronic kidney disease, attacks on the center, center failure, and the period between last vaccination and COVID-19 infection.
* Even when they had no other serious chronic conditions, other people with high blood pressure were 2. 6 times more likely to need hospital care for a serious illness similar to COVID-19.
* Of the 145 patients admitted to the hospital, 125 (86. 2%) had high blood pressure.
“We want to develop the wisdom and understanding that receiving 3 doses of the vaccine might not absolutely protect other people from the progression of severe COVID-19, especially in other people with high blood pressure. In addition, more studies are needed on the reasons for the relationship between high blood pressure and the increased risk of COVID-19 disease arising, according to Ebinger.
On how to lessen the dangers of a severe COVID-19 infection, whether through more specialized vaccine regimens, new treatments, or a combined strategy, the researchers indicated that more studies are needed. tension is another domain that researchers say requires further study.
The effects may not be generalizable because the researchers used information from a single doctor for retrospective analysis.
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