Analysis by Spanish and Peruvian researchers shows that maximum altitude provides significant coverage against coronavirus infection and death (COVID-19), regardless of the distance from the epicenter of the pandemic, population density or poverty levels. The scan is available lately on the medRxiv prepress server.
More than 700,000 international people have already lost their lives as a result of the PANDEmic COVID-19 caused by coronavirus 2 (severe acute respiratory syndrome) (SARS-CoV-2). Clearly, some countries have been more affected by the disease than others.
Although first saved, COVID-19 cases have increased significantly in Latin American countries recently. However, due to the lack of information on disorders and the relative scarcity of detailed data, only a few studies have tested the dynamics and express characteristics of the pandemic in South America.
But despite the lack of data in the early stages, knowledge accumulation now allows for much more detailed epidemiological analyses, which are required to communicate policies to populations at peak risk of contracting the disease.
In this new study, researchers from the National Council of Sciences (Barcelona), the National Institute of The Angels Health Carlos III (Madrid) and the Institute of Biocomputation and Physics of Complex Systems (Zaragoza) in Spain, as well as the Universidad Peruana Cayetano Heredia (Lima) in Peru, have followed an ecological technique to describe the existing status and dynamics of the pandemic in Peru.
Although previous studies have already warned that altitude would possibly be a protective factor against COVID-19, this retrospective research is the first to use a giant national longitudinal database covering all cases and deaths of COVID-19 recorded in Peru until July 17. 2020.
In order to determine the appropriate population density, which tends to be particularly compatible with that of coastal lowlands, researchers have standardized the number of cases/deaths across population density and according to the population of millions in all districts.
In addition, they took into account the prevalence of noncommunicable diseases (described through previous surveys) as an indicator of comorities related to the occurrence of fatal infections and outcomes.
“Our maximum applicable discovery is a significant arrangement between high-altitude life and a lower threat of COVID-19 contagion and disease death,” the authors write in their medRxiv paper.
The study also provides evidence that the recent outbreak of cases in the highest altitude districts in Peru can be explained through the influx of migrants from giant urban centers to higher-altitude districts in an express direction, which in turn outweighs the armor effect with all likelihood conferred. maximum altitude to the population of those specific districts.
The effects also reveal that the standardized mortality rate of COVID-19 is particularly correlated with the prevalence of higher blood pressure and cholesterol levels, as well as at low altitudes. However, COVID-19-related mortality rates are not particularly correlated with population density, despite an observed trend.
Finally, altitude coverage has been shown to be independent of poverty rates, meaning that altitude provides coverage opposite the onset and death of COVID-19, which is compensated even through the maximum poverty.
” We believe in the concept that the room/long-term exposure at higher altitudes protects against severe respiratory viral diseases, adding COVID-19, through multiple mechanisms prevalent in citizens or in genetically determined populations in populations adapted to chronic hypobaric hypoxia’, the study authors said. their findings in context.
These mechanisms come with anatomical, physiological and immune adaptations. In addition, it has been cautioned that environmental points (maximum ultraviolet radiation, low temperatures or low humidity) would possibly contribute to minimizing SARS-CoV-2 transmission at maximum altitudes.
However, translating this wisdom to expand effective remedies for COVID-19 will be difficult, as protective effects would possibly require long-term multi-ther adaptations. At the same time, there would possibly also be many subsequent consequences when managing parts of the reaction to hypoxia.
And caution is required, since adaptations at peak altitudes would possibly confer some degree of coverage opposite SARS-CoV-2 and COVID-19, but not a se-compatible immunity; therefore, all appropriate coverage steps should be followed diligently.
medRxiv publishes initial clinical reports that are not peer-reviewed and therefore should not be considered conclusive, the clinical practice of the health-related consultant/habit or be treated as established information.
Written by
Dr. Tomislav Me-trovio is a physician (MD) with a physicist. in biomedical and fitness sciences, specialist in the area of clinical microbiology and assistant professor at the youngest University of Croatia – University North. In addition to his interest in clinical activities and conferences, his immense hobby in medical writing and clinical communication dates back to his student days. He likes to contribute to the community. In his spare time, Tomislav is a filmmaker and a wonderful traveler.
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