(Reuters) – The following is a summary of some of the most recent clinical studies on the new coronavirus and efforts for remedies and vaccines that oppose COVID-19, the disease caused by the virus.
Large-scale genetic testing to identify populations vulnerable to COVID-19 would possibly be possible, according to French researchers. In exposing their speculations in trends in Genetics, they described two opposing enzyme procedures that occur when the coronavirus enters the framework. A procedure contributes to the infection by helping the virus enter cells. The other, an opposite procedure, protects the frame by moving the virus away from its target cells. Among individuals, they said, genetic differences are the strength of these infection and coverage mechanisms, and some other people have genes that predispose them to infection and others have genes that strengthen the framework coverage procedure. If a genetic threat score was developed based on data contained in genetic databases analyzed through the researchers, then populations at threat of COVID-19 severe “could be characterized through express genetic profiles,” examines Antoine Lacassagne Cancer Nice Cinput co-author Gerard Milano told Reuters. (bit.ly/3fYZA7W)
Care homes can be safer when staff live there
Compared to nursing homes in France where staff arrived and left during the coronavirus pandemic, the amenities where staff chose to confine themselves to citizens had lower rates of coronavirus infections among citizens and staff and fewer deaths from COVID-19 among citizens, according to research. In many countries, nursing homes have experienced a large number of deaths due to COVID-19, and other elderly people are occasionally vulnerable to disease. Investigators compared 17 nursing homes where staff were staying with citizens and 9,513 nursing homes where staff were leaving at the end of the shifts. Coronavirus infections evolved in a self-containment facility (6%) and in 4599 of the other establishments (48%), they reported on Thursday in jamA Network Open magazine. In self-employed establishments, the COVID-19 rate among citizens was 0.4%, compared to almost 4% in other households. Residents of establishments where staff members were self-employed were also 80% less likely to die from COVID-19. In addition, the rates of COVID-19 imaginable or shown were 2% among staff members who were held, compared to 8% of those returning home daily. The findings “suggest that self-containment of staff members with citizens would possibly help protect citizens from nursing homes,” the investigators said. “Staff members have done something out of the ordinary by limiting themselves to citizens” and “putting aside their private lives by staying on the premises for several weeks, at night and in the day,” examines co-author Dr. Joel Belmin de Pitié- Salpétriére. Reuters told the Charles Foix Hospital in Paris. (bit.ly/2Y3NlRo)
High transmission of the virus in homes
The biggest threat of coronavirus transmission is among others living together, a Test from China said. Earlier this year, Chinese researchers tracked 3,410 close contacts from 391 COVID-19 patients to determine the rate at which other inflamed people transmitted the virus. The so-called secondary attack rate was 0.1% on public transport and 1.0% on fitness services, where masking was mandatory, but was 10.3% in households. Secondary attack rates increase as patients’ symptoms have become more severe. In general, patients were nearly five times more likely to infect others if they spit mucus or mucus. Secondary attack rates in other countries would possibly be different because China has implemented strict quarantines and other measures to control the coronavirus outbreak. “However,” the researchers wrote Thursday in the journal Annals of Internal Medicine, “the threat of secondary infection through domestic contact was the highest compared to other tactile parameters, as other people spent more time at home, leading to a more common and prolonged infection. Unprotected infections. Exhibition. ” (bit.ly/2Y38ICt)
No effect on the placenta was observed with COVID-19 at the end of pregnancy
Coronavirus infection at the end of pregnancy does not resemble the microscopic design of the placenta, which is the key organ of pregnancy and fetal growth. Researchers tested third-quarter placentas of 21 women with COVID-19 and 20 women with negative coronavirus test results. Compared to women’s negatively controlled placentas for the virus, the placentas of inflamed women showed no differences in the arrangement of cells or tissues, or in blood flow problems, the authors reported in an article published on the medRxiv online page on Wednesday before the peer review. There were also no significant differences in placental weight or dating between placental and fetal weight, two signs of placental function. While coronavirus infections that occur earlier in pregnancy may have greater effects on the placenta, “our study suggests that COVID-19 infection in expired pregnancy (third trimester) would possibly not produce demonstrable pathology,” examined the test co-author, Dr. Mai He, of Washington University School of Medicine in St. Louis, told Reuters. (bit.ly/3gXi4an)
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Reporting through Nancy Lapid and Linda Carroll; Edited through Will Dunham
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