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The U.S. Food and Drug Administration (FDA) announced Sunday that it will now authorize emergency use of “convalescent plasma therapy” for patients hospitalized with coronavirus, a resolution that has brought hope and sparked debate.
Treatment, which involves injecting the liquid component of the blood containing antibodies from those that have recovered from the coronavirus, is considered safe. The first effects of a Mayo Clinic test showed that it could, in limited circumstances, stimulate the body’s immune formula to fight the virus, if administered early enough.
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However, this exam is still ongoing, and the knowledge published to date does not meet the widely established popularity of a peer-reviewed double-blind survey involving a placebo control group, as Mayo researchers themselves have easily recognized. Specifically, they reported that the seven-day mortality rate among the 35,000 patients, most commonly ill, who were refuted with remedy within 3 days of diagnosing COVID-19 was lower (8.7 percent consistent) than for patients transfused with remedy 4 days. after diagnosis. (11.9 consistent with one percent).
Cachay was one of many policy and science experts who rated FDA emergency use approval as premature, saying that the effects of smaller studies published so far show effects that are, at best, productive “marginal” and questioning the effectiveness of time-consuming treatment. “We want more extensive trials underway to answer questions. I hope this resolution has no effect on them,” he said.
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The use of convalescence plasma is not new; the Spanish influenza pandemic was used to save lives. In addition to the small trials here, it has been studied in patients with COVID-19 in China and the Netherlands.
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