Fauci: ‘Open America Again’ has thwarted COVID control

Random and inconsistent closures are an explanation for why the United States has never returned to a COVID-19 case base as the European Union has done, Anthony Fauci, MD, director of the National Institute of Allergy and Infectious Diseases, told a plenary convention at IDWeek Virtual.

In addition, Fauci supported the concept that COVID-19 is propagated through aerosols, saying that “we are pretty sure it plays a role. “

When launching IDWeek’s COVID-19 “Chasing the Sun” convention, Fauci’s convention was so busy that some attendees had trouble connecting and the convention had to provide an additional link on their Facebook account.

Addressing his clinical colleagues in infectious diseases, Fauci presented knowledge that contrasted COVID-19 instances in the United States with those in the EU, and where the two spaces differed.

First, both had a primary epidemic that included a giant proportion of cases (New York for the US) and the United States. But it’s not the first time And northern Italy for the EU), with the EU moving ahead of the EU, and the EU is ahead of the world. But Europe has returned to a very low benchmark. level, unlike the United States.

“Note that between April and June our baseline never exceeded 20,000, however, when we started [sic] what is called ‘us reopening’,” there was a “great inflection: accumulation in June, July, and August, when we went to about 70,000 instances consistent with the day. “

Today, the United States records between 50,000 and 60,000 a day, he noted.

The explanation of why we don’t stick to Europe’s trajectory for the “people movement,” Fauci said. Knowledge of GPS showed that visits to parks and outdoor spaces did not minimize in both the United States and Europe, he said, neither in workplaces, grocery stores or pharmacies.

While the virus spreads mainly in close interaction with inflamed people, Fauci said, “recent evidence” indicates that more remote and brief encounters can also lead to aerosol transmission (usually explained as debris less than five m).

It is not known what proportion of transmissions occur from this route, he said.

He noted that while “contaminated surfaces” play a role in the transmission of physical fluids, such as blood, urine and semen, “the role of transmission is unknown and not as important. “

Fauci cited the knowledge that the case rate of COVID-19 cases in the US was not the only one in the world. But it’s not the first time It is 2. 3%, but can reach 20 to 25% for other people who require mechanical ventilation. He discussed ongoing studies on other manifestations of serious illnesses.

While Acute Respiratory Difficulty Syndrome (SED) is the most common, “as we gain clinical experience, we see more protein manifestations that would possibly occur, such as a heart disorder related to heart inflammation” that can lead to arrhythmias, cardiomyopathy, and sudden death.

When he referred to the gigantic racial and ethnic disparities in COVID-19 infections, Fauci cited not only the comorities in these populations, but also the concept that they have jobs that “put them on the front line, so they are exposed to the virus. . ” much more than the general population. “

Looking ahead, he addressed the role of “experimental therapies” in the treatment of COVID-19 in its early stages, characterizing convalescent plasma as providing “quite encouraging results, which have not yet been achieved in clinical trials” and monoclonal antibodies as “quite promising”. “”

He reiterated the hope that either on the “number of infections in the country and the distribution of control sites”, as well as on “animal studies and early immunogenicity studies”, there will be a “response” to whether we have an effective vaccine against SARS-CoV-2 from mid-November to early December.

Fauci also discussed the role that NIH has played in the process, adding a “harmonization protocol” with a singles protection and knowledge monitoring committee for all ongoing core trials, as well as “non-unusual secondary and number one evaluation criteria and parameters to be used as immunity correlates. “

Molly Walker, associate editor-in-chief, covering infectious diseases for MedPage Today, is passionate about evidence, knowledge and public health.

IDWeek is co-sponsored by the American Society of Infectious Diseases, the American Society of Health Care Epidemiology, the HIV Medicine Association, the Pediatric Infectious Diseases Society, and the Society of Infectious Disease Pharmacists.

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