Scientists from the National Institute of Public Health and Environment in the Netherlands conducted a study to explore the efficacy of vaccination against coronavirus disease 2019 (COVID-19) in preventing disease-like hospitalizations.
The study, recently available on the preprint server medRxiv*, shows that COVID-19 vaccination prevented a large number of hospitalizations during the pandemic.
The COVID-19 pandemic through severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has particularly affected the global fitness system, with more than 650 million infections and more than 6. 66 million deaths worldwide. the world. However, with the rollout of COVID-19 vaccines, there has been significant relief in cases, hospitalizations, and deaths.
Up to August 2022, the Netherlands had detected 8.5 million COVID-19 cases, resulting in 113,000 hospitalizations and 22,000 deaths. Since the initiation of COVID-19 vaccination programs in January 2021, more than 36 million vaccine doses have been administered in the country.
In the existing study, scientists estimated the number of COVID-19 hospitalizations averted with vaccines in the Netherlands. This would make the general population and policymakers realize the importance of COVID-19 vaccination.
The number of COVID-19 hospitalizations averted with COVID-19 vaccination estimated from January 6, 2021, through August 30, 2022 (first review period). The estimate was also made from 2 August 2021 to 30 August 2022 (second review period). During this period, all adults had the opportunity to get the number one series and young people aged 12 to 17 became eligible for vaccination.
We estimated the number of hospitalizations avoided through age organization, vaccine efficacy estimates, vaccination policy estimates (primary and booster shots), and the observed number of COVID-19 hospitalizations. The absolute and relative numbers of hospitalizations avoided were estimated for each time period examined. in which a viral variant was dominant.
A change in the first immunization policy was observed at the end of the study period. Coverage ranged from 73% for the 12 to 49 age group to 94% for the 70 to 79 age group.
The vaccination policy for the first booster dose ranged from 42% for the 12-49 year old organization to 88% for the 70-79 year old organization. For the booster dose, the vaccination policy ranged from 0% for the 12-49 age organization to 67%. for the organization from 70 to 79 years old.
In general, the vaccination policy is higher in older teams than in younger ones.
During the entire study period, a total of 98,170 hospitalizations have been prevented thanks to COVID-19 vaccination. Most of these hospitalizations (90,753) were avoided during the second study period (August 2, 2021 to August 30, 2022).
COVID-19 vaccination was estimated to prevent 57% and 67% of all hospitalizations in the first and second study periods (January 2021 to August 2022), respectively.
The number of hospitalizations avoided was higher in the 70- to 79-year-old organization and lowest in the 12- to 49-year-old organization.
During the era when the alpha variant of SARS-CoV-2 was dominant, approximately 8% of all hospitalizations were prevented through vaccination. During the delta and omicron waves, respectively, approximately 72% and 63% of all hospitalizations were prevented through vaccination.
The study highlights the importance of COVID-19 vaccines in preventing COVID-19 hospitalizations. The greatest positive effect of vaccination was observed in people aged 70 to 79 years during the Delta variant outbreak.
As mentioned by the scientists, such a vaccine-mediated reduction in hospitalization rate has reduced the pressure on hospitals and healthcare workers and improved access to healthcare facilities for both COVID and non-COVID patients.
Written by
Dr. Sanchari Sinha Dutta is a science communicator who believes in spreading the power of science to each and every corner of the world. He holds a Bachelor of Science (B. Sc. ) and a Master of Science (M. Sc. ) in human biology and physiology. After earning his master’s degree, Sanchari continued his doctoral studies. in human physiology. She is the author of more than 10 original study articles, all published in world-renowned foreign journals.
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