By Nancy Lapid
(Reuters) – The following is a summary of some of the most recent clinical studies on the new coronavirus and efforts to remedy and vaccines that oppose COVID-19, the disease caused by the virus.
Positive tests related to the COVID-19 restaurant
Among adults who have been tested for coronavirus at 11 fitness services in the US, it is not a problem that has been tested for coronavirus. But it’s not the first time In July, those who were inflamed were about twice as likely to have dined at a place to eat in the past 14 days, according to a US study. U. S. in others with or without COVID-19 in other respects. These include shopping, social gatherings at home, trips to an office, living room or gym, use of public transportation or participation in devout meetings. “Masks can’t be used well while eating and drinking, while shopping and many other indoor activities don’t save you from wearing a mask,” the researchers said in Friday’s report on the US Centers for Disease Control and Prevention’s weekly morbidity and mortality report. “Nice stay” Site entries with such features can be threat points related to SARS-CoV-2 infection,” they added.
COVID-19 severe less common in patients with gastrointestinal symptoms
People with gastrointestinal symptoms related to the new coronavirus, such as diarrhea, nausea and vomiting, would likely be less likely to spread severe COVID-19 and die, according to a new study. Doctors in New York City evaluated 635 COVID-19 patients, expecting to see worse illness when the digestive tract was involved. To their surprise, patients admitted with gastrointestinal symptoms were 50% less likely to have severe COVID-19 and death, compared to patients without gastrointestinal symptoms, even taking into account age and condition. race and underlying medical conditions. Also unexpectedly, the patients with gastrointestinal disease had reduced levels of inflammatory proteins in their blood. A subset that underwent a closer inspection of their intestines had viral debris in their gut tissue, but little inflammation and low activity in genes responsible for making inflammatory proteins, the doctors found, according to an article published Wednesday in medRxiv before peer review. When doctors in New York collaborated with Italian colleagues to examine 287 COVID-19 patients in Milan, they saw the same link between gastrointestinal involvement and less severe illness, said Dr. Saurabh Mehandru of the Icahn School of Medicine at Mount Sinai. Mehandru’s team also found that taking gastrointestinal symptoms into account in the initial evaluation of the patient can help identify those who are at risk for a more serious illness.
Antibody binding may not “neutralize” the virus
A so-called spike protein on the surface of the new coronavirus is helping it invade cells, and some remedial-proven antibodies paint by sticking to the spike and turning it off. But researchers have discovered in test tube experiments that the undeniable binding to the spike protein is not necessarily sufficient to “neutralize” the virus’s ability to break down in cells. When they exposed coronavirus debris to the antibody-rich plasma of 25 other people recovering from COVID-19, all the antibodies bound to the spike protein. However, some plasma samples failed to neutralize the virus and were no more effective than plasma from other uninfected people. The findings may help explain why convalescent plasma treatment doesn’t work, the researchers say. They did not use active viral waste for their experiments. Still, exam leader Andres Finzi of the University of Montreal told Reuters the effects underscore a desire to be more informed about the other bureaucracy that can take the spike protein when the virus enters cells and how. block them. “Efforts to better understand the link between the interaction of antibodies with the spike protein and virus neutralization may simply aid ongoing vaccination efforts aimed at obtaining neutralizing antibodies,” the researchers conclude in a paper published Tuesday. on bioRxiv prior to peer review.
The new formula combines hospitalized patients with COVID-19 through risk
An undeniable 21-point scoring formula is used to assign COVID-19 hospital patients to other threat organizations, British researchers from the BMJ reported Wednesday. “Sheet music doesn’t require an app or any other technology, beyond maybe a pen or pencil if you can’t count to 21 in your head,” said Dr. Calum Semple. from the University of Liverpool to Reuters. The score takes into account 8 factors, in addition to age, other diseases, kidney condition, and blood oxygen levels. Based on the result, patients are assigned to one of 4 organizations. The threat of dying from COVID-19 is 1% in the low threat organization, 10% in the intermediate threat organization, 31% in the top threat organization, and 62% in the top threat organization. The ISARIC Coronavirus Clinical Characterization Consortium developed its knowledge of the “4C” scoring formula for 35,463 patients and validated its accuracy in another 22,361 patients. As pressures on fitness facilities mount, it’s especially important to be able to identify patients who are likely to want extensive care, Semple said in a news release. The tool is online at isaric4c. net/threat.
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(Report via Nancy Lapid; Edited through Bill Berkrot)