COVID infection may have an effect on sperm quality in men, according to an AIIMS study

However, little information is available on the excretion of SARS-CoV-2 in semen, the thick, white fluid containing sperm, and its effect on sperm formation and fertility potential.

The study, published in the Cureus Journal of Medical Science, investigated the presence of SARS-CoV-2 in the semen of men with COVID-19. The researchers also looked at the disease’s effect on sperm quality and sperm DNA fragmentation rate, reflecting DNA integrity and damage, thus detecting potential sperm damage.

Thirty male COVID-19 patients aged 19-45 registered at AIIMS Patna Hospital participated in the examination between October 2020 and April 2021. “We performed real-time opposite transcriptase verification on all semen samples. Detailed semen analysis, adding sperm DNA fragmentation index, the first sampling was performed, i. e. COVID-19,” the examination authors said.

“After 74 days of the first sampling, we were given the sampling on the spot and repeated all the tests,” they said. tested with real-time opposite transcriptase polymerase chain reaction (RT-PCR) were negative for SARS-CoV-2.

In the first sample, semen volume, vitality, overall motility, sperm concentration and overall sperm count were lower, the researchers said. WBCs or white blood cells increased.

Liquefaction time is a measure of the time it takes for sperm to become liquid, while viscosity is the thickness of seminal fluid. These effects were reversed at sampling time but at the optimal level, according to the researchers. The effects were statistically significant, suggesting that “COVID-19 negatively affects sperm parameters, adding the sperm DNA fragmentation index,” the authors ed.

“Although we may not simply locate SARS-CoV-2 in semen, sperm quality remained poor up to the time of sampling,” they said. COVID-19.

ART includes all fertility remedies in which eggs or embryos are manipulated. These clinics exclude men with a positive history of SARS-CoV-2 until their sperm quality returns to normal, the researchers added.

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