COVID-19 withdrawals tolerated by pregnant and lactating women

COVID-19 booster injections are well tolerated by pregnant and nursing women, concluded a new article published Sept. 8 in JAMA Network Open.

The UW Medicine-led study with more than 17,000 participants showed that “there were very few obstetric disorders after the patients won the reminders,” noted the leader and Dr. Lisa Schoen. Alisa Kachikis, OB-GYN UW Medicine.

In addition, the American College of Obstetricians and Gynecologists today issued a practice notice encouraging pregnant or nursing women to obtain the most recent COVID-19 recall, which has been changed to protect themselves from the BA. 4 and BA. 5 variants. This reminder has become to have last week.

This vaccine will be for everyone else who has two months since their last booster. And if you’re pregnant, that includes you. If you’re in the postpartum period, that includes you. “

Eckert said the study confirms the importance of pregnant and nursing women getting their boosters. Eckert, a professor of obstetrics and gynecology at the University of Washington School of Medicine, was the leader of the study.

“Most of the pregnant and nursing participants did very well with the COVID-19 withdrawal. In fact, most participants reported that symptoms with the booster or third dose were less severe than symptoms with their initial series of COVID-19 vaccines,” Kachikis added.

As such, it is vital that number one care providers continue to submit the initial circular of vaccines and boosters for pregnant and lactating women, he said. The effects of this study are applicable now that the new COVID-19 withdrawal is appropriate. more widely available this month, he added.

Kachikis and his team gathered information from a follow-up survey that was sent to just over 17,500 participants last October. These participants were part of an ongoing cohort survey to monitor pregnant and lactating women’s reaction to the initial vaccine and, in this study, booster shots.

Just over 97% of the cohort responded to the follow-up recall survey. In this cohort group, 11% were pregnant; 60% were breastfeeding and 27% were not pregnant or breastfeeding at the time of the survey. The majority (82%) reported pain at the injection site; with 68% reporting symptoms such as fatigue or fever

Importantly, when it came to a recall or a third dose of COVID-19, pregnant participants were more likely to cite their physical care provider as a source of information and to have obtained advice on obtaining a recall. This suggests that doctors may play a role in vaccine acceptance and as a source of vaccine data.

The original test, introduced in January 2021, designed to monitor the reaction of pregnant and lactating women to the first COVID-19 vaccines. The average age of the organization is 33, with 92% of the organization identifying as white and 99% identifying as female. When Kachikis designed this online cohort study of women, it included those who were pregnant or breastfeeding and those who were not pregnant or breastfeeding.

This online cohort follow-up study, as it receives booster doses, continues to find that pregnant and nursing women tolerate COVID booster vaccines well and that they deserve to be included in clinical trials for other applicable vaccines, Eckert said.

Aside from the CDC’s vsafe registry, this is the largest U. S. study. U. S. Department of Homeland Security on this topic. Canada has created a record in the Kachikis version.

According to the CDC, 71. 3% of pregnant women in the United States obtained at least the first COVID-19 vaccine circular before pregnancy. Acog estimates that 55% obtained a recall. This study reassures pregnant and nursing women who want to receive a booster dose. Kachikis hopes this study, along with other reassuring studies, will inspire pregnant and nursing women to get boosters and vaccines, if they haven’t already.

This study was conducted through the National Center for the Advancement of Translational Sciences (UL1 TR002319) and the Women’s Reproductive Health Research Award of the National Institute of Child Health and Human Development (2 K12HD001264-21) with the aim of designing and conducting the study; collection, management, studies and interpretation of knowledge. The University of Washington Translational Health Sciences Institute provided administrative to electronic knowledge capture studies for this assignment and it was edited through NCATS grants UL1 TR002319, KL2 TR002317, and TL1 TR002318.

The content of the review report is the sole responsibility of the authors and necessarily constitutes the official perspectives of the National Institutes of Health.

University of Washington School of Medicine

Kachikis, A. , et al. (2022) Analysis of vaccine reactions after booster doses of COVID-19 vaccine in pregnant and lactating women. JAMA ouvert. doi. org/10. 1001/jamanetworkopen. 2022. 30495.

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