Now, some are starting or reaching the last level of testing.Depending on the results, some corporations say their vaccines may receive the green light as soon as this year.
The precursors
Among the first vaccine applicants to start the new test circular is one developed through the University of Oxford and AstraZeneca PLC.Pfizer’s experimental plans include your spouse BioNTech SE, as well as Moderna Inc.
China National Pharmaceutical Group Co., or Sinopharm, has a phase 3 vaccine.A vaccine from the Chinese company CanSino Biologics is expected to begin key testing soon, but remember, many promising vaccines in early testing fail in the final phase.
The Oxford/AstraZeneca vaccine is designed to provide coverage by delivering the genetic code of the peaks protruding from the new coronavirus in a person’s cells. The cells can then produce complex proteins, generating an immune reaction that would be to fight the coronavirus.these genetic commands are a weakened and innocent edition of a virus that causes colds in chimpanzees.
In early tests, the vaccine was able to produce immune responses in humans with only minor side effects.A phase 3 trial with 30,000 subjects was initiated in the United States in August.Other complex trials are being conducted with several thousand volunteers in the UK, Brazil and South Africa.
Estimated production capacity: AstraZeneca aims to make two billion doses internationally and said that perhaps one billion will only be available this year.
The Modern vaccine also uses gene-based generation to boost an immune response, the code that delivers takes the form of messenger RNA.These molecules, commonly known as mRN, are the body’s molecular e-mails that carry DNA commands to produce proteins.cells to produce the complex coronavirus protein.
And the U.S. National Institute of Allergy and Infectious Diseases.But it’s not the first time They’re testing a two-dose injection, which was the first candidate to introduce human controls in the United States.minor side effects observed in control subjects.
Final phase testing is underway in the United States with a test of another 30,000 people who may produce interim effects in the fall.An mNR vaccine has never been approved for any disease.
Estimated capacity: 500 million to one billion doses in line with the year from 2021.
The vaccine evolved through Pfizer and its German spouse BioNTech SE also uses mr.A.In a phase 1 trial, the vaccine generated neutralizing antibodies that promise to fight coronavirus and was sometimes well tolerated.recruiting about 30,000 people, and will expand to reach approximately 120 sites.
The U.S. government has not been in the process of Hus He agreed to pay Pfizer and BioNTech nearly $2 billion per hundred million doses.Pfizer is the regulatory approval or approval of emergency use in October.
Estimated production capacity: up to one hundred million international doses by the end of 2020, and about 1.3 billion by the end of 2021.
China’s state-owned Sinopharm is preparing two vaccines with the Wuhan Biological Products Institute government agencies and the Beijing Institute of Biological Products, both in an older vaccine production technique.
The organization has signed testing agreements in several countries, Pakistan and the United Arab Emirates.Wuhan Institute has drawn attention to its protective history, some of its vaccines for children.
The government says it has begun what it calls “emergency use” of some of its Covid-19 vaccines in the medical corps of workers and border inspection officials in late July.
Estimated capacity: about 220 million doses in line with the year.
Sinovac, a Chinese personal company, began its final trial in July in Sao Paulo, Brazil, where it is testing its vaccine to take advantage of a higher infection rate. Sinovac also signed an agreement with the Indonesian state pharmaceutical company PT Bio Farma to manufacture up to 250 million doses of vaccines a year for the Indonesian public, according to China’s official news agency.
Estimated production capacity: about three hundred million doses according to each year at a plant in Beijing.
The CanSino vaccine is originally intended for the Chinese army.The Chinese company CanSino developed the shooting with the military on the basis of a weakened virus, the cold.A phase 1 phase 1 review was conducted in March in Wuhan, the first epicenter of Covid-19.The shooting was approved by the government in June for use by the army for a year.
Estimated production capacity: one hundred to two hundred million doses consistent with the year from 2021.
Johnson
Estimated production capacity: one billion international until the end of 2021, adding one hundred million doses for the United States, with an option to another two hundred million, and 30 million doses for the United Kingdom, with an additional acquisition option of up to 22 million.
The Russian Public Research Institute Gamaleya is developing a vaccine based on a mixture of two adenoviruses, which it has already tested in volunteers.Russia approved the use of the vaccine in early August, the vaccine was not tested in the final stage.The Russian government plans to begin mass vaccination in October and will aim to deploy in high-risk groups, adding fitness workers.
Estimated production capacity: 500 million doses according to each year, with mass production in September 2020.
The US company Novavax Inc.manufactures a vaccine consisting of two injections over a 21-day period that deliver proteins that resemble the protruding tip of the new coronavirus, and researchers expect proteins to cause the production of antibodies and immune cells capable of combating coronavirus.
Injections also involve a component, called an adjuvant, to stimulate immune response.In Phase 1 tests, the vaccine was well tolerated and produced a promising amount of antibodies.Phase 2 testing began in August and the company said Phase 3 could begin.September.
Estimated production capacity: one hundred million doses for use in the United States, with delivery from the end of this year.Manufacturing plans for other countries.
This story was published from a firm thread without converting the text.
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