Analyzing the most comprehensive datasets in the United States, researchers at Mount Sinai’s Icahn School of Medicine found that COVID-19 vaccination is linked to fewer heart attacks, strokes, and other cardiovascular disorders in others infected with SARS-CoV-2, the virus that causes COVID-19.
The study letter, “Impact of vaccination on major adverse cardiovascular events in patients with COVID-19 infection,” was published in the Journal of the American College of Cardiology on Feb. 20.
In addition, the studies will be presented at a poster consultation in New Orleans, LA, the 72nd annual scientific session of the American College of Cardiology with the World Heart Federation World Congress of Cardiology:
Poster session
Title – Prevention and Health Promotion: Population Sciences
Date/Time: March 5, 2023, 9:30 a. m. to 10:30 a. m. m. *Central Time*
Location – Poster Room, Room F
This is the first study I read about full and partial vaccination and the link to primary adverse cardiac events (MACEs) in the United States, confirming similar analyses conducted in the past with the Korean COVID-19 registry. The researchers used the Cohort Collaborative’s (N3C) National COVID Knowledge Base, the largest comprehensive national knowledge base on COVID-19. Since its inception in 2020, the N3C has frequently collected and harmonized knowledge of institutional e-fitness registries at the national level. This study included 1,934,294 patients, 217,843 of whom won the Pfizer-BioNTech or Moderna mRNA vaccine formulations or Johnson’s viral vector generation.
We tried to explain the effect of previous vaccination in cardiovascular cases on other people who contract COVID-19 and found that namely in other people with comorbidities, such as anterior MACE, type 2 diabetes, high cholesterol, liver disease, and obesity, there is a settlement with a lower threat of complications. While we cannot characterize causation, this is evidence supporting that vaccination can have favorable effects on a variety of post-COVID-19 complications. “
“To our surprise, even partial vaccination was associated with a lower threat of adverse cardiovascular events,” said study author Joy Jiang, a candidate in Dr. Nadkarni’s lab. “Given the scale of SARS-CoV-2 infection worldwide, we hope our findings may help vaccination rates, especially among others with coexisting diseases. “
Further studies will be needed to elucidate the mechanisms involved from an immunological point of view and explain the role of SARS-CoV-2 subtypes and reinfections in dating to MACE risk.
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