Research by the Oswaldo Cruz Foundation (Fiocruz), which analyzed the four vaccines administered in Brazil against COVID-19 from January to October 2021, shows that all of them offer great relief from the risk of infection, hospitalization and death.
Taking into account severe outcomes (hospitalization or death) in older Americans aged 20 to 80 years, coverage ranged from 83% to 99% for all immunization providers. In the 60-year-old population, all vaccines offer more than 85% coverage, unlike the threat of hospitalization, and more than 89% oppose the threat of death.
The data can be found in the first edition of the bulletin on the efficacy of vaccines against covid-19 in the Brazilian population, from the Vigivac mission in Fiocruz, on Thursday (9).
The analyses, coordinated by researcher Manoel Barral, from Fiocruz Bahia, were carried out with anonymous individual data from the databases of the National Vaccination Campaign against Covid-19 (Covid-19 Vaccination), notifications of influenza-like illnesses (e-SUS Notifica) and reports. Severe Acute Respiratory Syndrome (SARAG 2020 and 2021; SIVEP-Influenza).
According to the survey, CoronaVac showed peak efficacy for the older population aged 18 to 59, ranging from 89% to 95% and from 85% to 91% for deaths and hospitalizations, respectively. However, there is a significant decrease in efficacy in other older people. 60 years and older. Between the ages of 60 and 69, coverage against serious illnesses is 81%, rising to 64% for the rest of people over 80 years of age.
The researchers say that this relief in coverage in the elderly is explained by several factors, but mainly by the longer time that has elapsed since the last vaccination and by the greater vulnerability of the organization that won the immunizer, since CoronaVac was the maximum used among the elderly. and they precede professionals, such as those in the area of fitness and security, who are more exposed to contagion. In addition, the vaccine was administered at a time of increased viral circulation.
AstraZeneca was the most widely used vaccine in the country, according to the bulletin. The results for the adult population up to 59 years of age showed a 99% efficacy of the immunizing agent against death. The decrease in potency is also accompanied by an increase in the age range. In the 60-69 age group, coverage against infection was 89 percent, rising to 82 percent in Americans over 80. In terms of deaths, the rest of people over 80 years of age had a coverage of 91%. less than the other teams for seniors aged 60 to 69 and 70 to 79, which had coverage of 97% and 93%, respectively.
Analyses of the older adult population aged 59 and younger who won Pfizer showed that coverage remained above 96%. Protection against death and hospitalization from COVID-19 in this organization was 99%. The researchers note that Pfizer administered to a younger population and at an epidemic time with less fluency of the virus, which may simply herald the vaccine’s efficacy.
In the adult population under 59 years of age that won Janssen, analyses indicated a coverage against death of 78% to 94%. Protection against hospitalization ranged from 88% to 91% and against infection, efficacy ranged from 68% to 73%. %. For the elderly population, it was only conceivable to estimate with certainty the efficacy for the population aged 80 years and over, which had 91 per cent coverage against death and 93 per cent coverage against hospitalization.
Translated text: synthetic intelligence.
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