The exam recently published in Respiratory Physiology – Neurobiology.
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Researchers studied cases of COVID-19 in the upper and lower regions of Bolivia, Ecuador and the Tibetan region of China.
Bolivia is one of the last countries affected by the pandemic, and one third of its territory extends to the highest heights. Meanwhile, the pandemic is profoundly affecting Ecuador and part of its population lives in high-altitude areas. On the other hand, the peak of the epidemic is over for the Tibetan region.
Scientists say the general prevalence of COVID-19 infection in Tibet doesn’t correspond to global trends. The region’s average elevation is 4,000 meters, or about 13,000 feet.
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The study authors also noted a “remarkable low infection rate” in Bolivia’s high-altitude population, which controlled the rates of exponential infection observed in many other countries. They found that COVID-19 infection rates in high-altitude areas in Bolivia are approximately 3 times lower than those in the lowlands, and 4 times fewer cases of COVID-19 in high-altitude areas in Ecuador.
The test reports noted that a clear indication of viral decline has an effect and infection among populations living at 3000 meters, or 9842 feet, above sea level.
Finally, the researchers also found that high-altitude citizens explicitly reduced the degrees of ACE2 in their lungs, a key union for the virus. The test authors concluded that minimizing ace2 expulsion into pulmonary endothelial cells could have given these populations some coverage against the virus.
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Researchers also theorized that ultraviolet radiation at high altitudes can act as an herbal disinfectant.
In general, the physiological acclimatization of the population at high altitude and the safe environmental characteristics have been concluded with the virulence of SARS-CoV-2.