The first set of instances was strongly grouped around the Huanan market; while the following cases were widely dispersed in Wuhan.
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New studies link COVID-19 with sales in the Chinese market. In addition, studies indicate that choice scenarios are incredibly unlikely. These studies come from the University of Arizona.
The studies use knowledge of location and viral sequencing for early cases of COVID-19. This painting shows that the pandemic began in the Huanan market in Wuhan, China, with live animals sold in the market as the most likely source. Here, foxes, Viverrin dogs and other live mammals vulnerable to the virus were sold alive just before the pandemic began.
Studies have eliminated all other possible sources of origin of the pandemic. The researchers say evidence indicates that the first animal-to-human spread likely occurred on two separate transmission occasions in the Huanan market in late November 2019.
This is based on knowledge of the location of the first known cases of COVID-19, as well as swabs taken from surfaces in various problems in the market. Organization that month, adding 155 in Wuhan.
In addition, genomic studies help the discovery that the SARS-Cov-2 virus has jumped to humans twice. This is taken from samples taken from COVID-19 patients in the first weeks of the pandemic in China.
After the initial infections, the first set of instances was largely clustered around the Huanan market; while the following cases were widely dispersed in Wuhan, a city of 11 million people.
In particular, a large number of the first COVID patients with no known connection to the market lived near the market. This confirms that the market is the epicenter of the epidemic. However, as the pandemic progressed, the newer cases matched the spaces of the higher population density in Wuhan.
The data answers the question of whether the health government has found cases in the market because that is where they looked. The first cases of other people who were converted and hospitalized were those who worked in the market.
The examination also analyzed swab samples taken from market surfaces, such as floors and cages, after the closure of the Huanan market. This revealed that places that tested positive for SARS-CoV-2 were particularly related to stalls promoting live wild animals. In particular, there was a clear agreement with the western part of the market, where live or freshly slaughtered animals were sold at the end of 2019.
The studies appear in the journal Science, titled “Huanan’s seafood wholesale market in Wuhan was the first epicenter of the COVID-19 pandemic. “
In similar research, the same team combined epidemic modeling with analyses of the early evolution of the virus based on the first genomes sampled. This showed that the pandemic, which first referred to two subtly distinct lineages of sars-CoV-2, most likely originated from at least two separate human infections of animals in the Huanan market in November 2019 and in all likelihood in December 2019.
To derive from this assessment, the scientists used a strategy called molecular clock analysis. This is based on the rate of herbs at which genetic mutations occur over time, to identify a framework for the evolution of SARS-CoV-2 virus lineages.
This article of current studies also appears in the journal Science, with the article entitled “The Molecular Epidemiology of Multiple Zoonotic Origins of SARS-CoV-2”.