Coffee is the most fueled beverage at the moment in the world, behind water. It is believed that the caffeinated beverage first entered Europe in the fourteenth century; Today, it feeds widely on the block.
In France, it is estimated that 94% of the population drinks coffee. But it’s Finland that takes the cake for being the world’s largest coffee consumer, according to one claim: the average Finn typically drinks around 4 cups of coffee a day.
While those 4 cups of coffee, and the 10-minute coffee breaks legally required in Finland for staff, are unlikely to be similar to the potential beverage-related fitness benefits, a recent influx of studies suggests that coffee intake provides a host of benefits: from maintaining the level of hypoglycemia to prospectively protecting against COVID-19.
The old fears around the negative health consequences related to coffee intake, basically due to its caffeine content, are now dispelled.
“Caffeine is just one of the many parts of coffee and not the only one that plays an active role,” explained Arrigo Cicero, a professor at the Department of Medical and Surgical Sciences at the University of Bologna in Italy. “We know that caffeine can increase blood pressure, but other bioactive components of coffee seem to counteract this effect with a positive end result in blood pressure levels. “
“This is the first to practice this arrangement in the Italian population, and the knowledge verifies the positive effect of coffee intake on cardiovascular risk,” added Professor Claudio Borghi, who led the publication in the educational journal “Nutrients”.
Earlier this year, in January 2023, researchers in Copenhagen also turned their attention to coffee’s potential fitness, but when fed milk.
In a paper published in the “Journal of Agricultural and Food Chemistry,” researchers from the Department of Food Sciences, in collaboration with researchers from the Department of Veterinary and Animal Sciences at the University of Copenhagen, found that a mixture of proteins and antioxidants duplicates the anti-inflammatory houses of immune cells.
Researchers had already shown that polyphenols, found in gigantic amounts in coffee beans, bind to milk proteins. “Our effects demonstrate that the reaction between polyphenols and proteins also occurs in some of the café-au-lait drinks we studied,” said Professor Marianne Nissen. Lund, from the university’s Department of Food Sciences. “In fact, the reaction happens so temporarily that it’s been difficult in any of the foods we’ve studied so far. “
The challenge is that humans do not absorb gigantic amounts of polyphenols without the presence of proteins. As a result, researchers are reading how to encapsulate polyphenols in protein structures for absorption into the body.
“This strategy has the added advantages of editing the anti-inflammatory effects of polyphenols,” explained Prof. Lund.
In Germany, coffee has gained renewed in the wake of the COVID-19 pandemic.
Researchers at Bremen’s Jacobs University have discovered that the chemical compound 5-caffeolyquinic acid, also known as chlorogenic acid, found in coffee, inhibits the interaction of a thing in 50 between the SARS-2 spike protein of the coronavirus and the ACE-2 receptor, the virus’ docking site to the human cell.
A cup of normal light coffee has about 100 mg of 5-caffeoliquinic acid, which, according to laboratory research, is a high enough concentration to prevent the spike protein from attaching to the ACE-2 receptor and thus also inhibiting infection. process.
Drinking a cup of coffee in a natural environment has not yet been proven to be an effective way to fight coronavirus infection. But at least, researchers say it’s plausible.
“As chemists, we cannot answer the practical question of whether coffee consumption can serve simply as a preventative measure to protect against infection. But we can say it’s plausible,” said Nikolai Kuhnert, a professor at Jacobs University. Other people drink coffee and it’s well established that it has many other positive effects. “
As for the next steps, the professor believes that epidemiological studies can determine whether normal coffee drinkers are more inflamed with COVID-19 or not.
According to a study conducted in Portugal, the possible physical fitness benefits related to coffee consumption are the alleviation of the severity of non-alcoholic fatty liver disease (NAFLD) in other people with type 2 diabetes.
The study, published in the journal “Nutrients” and sponsored by the Institute for Scientific Information on Coffee (ISIC), whose members are the large coffee companies Illycaffè, Lavazza and Nestlé, is the first to compare the possible independent mechanisms of caffeine and caffeine non-components to the severity of NAFLD.
Researchers at the University of Coimbra found that study participants who ate more coffee had healthier livers. Those with higher caffeine levels were less likely to have liver fibrosis, while those with higher levels of caffeine-free coffee parts were “significantly” linked. with reduced fatty liver index scores.
“Due to adjustments in nutrition and fashionable lifestyle, rates of obesity and the onset of type 2 diabetes and NAFLD are piling up, which can progress to more serious and irreversible conditions, weighing on fitness systems,” said John Griffith Jones, a principal investigator at the Center for Neuroscience and Cell Biology at the University of Coimbra. Portugal.
“Our studies are the first to practice that higher cumulative amounts of caffeine and non-caffeinated metabolites in urine are linked to lower NAFLD severity in other obese people with type 2 diabetes. “
However, not all this is good news for the famous drink. In December of last year, a study published in the “Journal of the American Heart Association” linked drinking two or more cups of coffee a day to twice the risk of death. From cardiovascular diseases in other people with severe hypertension, to non-coffee drinkers. . .
By contrast, the researchers found that a cup of coffee, and green tea intake, did not increase the risk of cardiovascular disease-related death through any measure of blood pressure, even if any of those drinks contain caffeine.
“Our study pointed to whether coffee’s known protective effect also applies to other people with other degrees of hypertension; and also looked at the effects of green tea on the same population,” said study lead author Hiroyasu Iso, director of the Global Health Policy Research Institute at Japan’s National Center for Global Health and Medicine.
“To our knowledge, this is the first study to find a correlation between intake of two or more cups of coffee and cardiovascular disease mortality in other people with severe hypertension. “
This may also mean that other people with severe high blood pressure deserve to avoid drinking too much coffee, ISO added. “Because other people with severe high blood pressure are more susceptible to the effects of caffeine, the destructive effects of caffeine would possibly outweigh its protective effects and possibly increase the threat of death. “
Sources: Self-reported coffee consumption of Nutrients and central and peripheral blood pressure in the Brisighella Heart Study cohort. Published on January 8, 2023. DOI: 10. 3390/nu15020312.
Journal of Agricultural and Food Chemistry’Phenolic acid and amino acid adducts exert distinct immunomodulatory effects on macrophages to generate phenolic acids’Published January 30, 2023DOI: https://doi. org/10. 1021/acs. jafc. 2c06658Autores: Jingyan Liu, Mahesha M. Poojary, Ling Zhu, Andrew R Williams and Marianne N. Lund.
Diet and function’Research on the interaction between polyphenols, SARS-CoV2 spike protein and ACE-2 receptor’Published on June 23, 2022DOI: https://doi. org/10. 1039/D2FO00394EAutores: Dorothea Schmidt, Inamullah Hakeem Said, Nicholas Ohl, Mobinassadat Sharifii, Paula Cotrell and Nikolai Kuhnert.
Increased nutrient intake of caffeine and caffeine-free coffee parts is linked to a relief in NAFLD severity in subjects with type 2 diabetes. John G. Jones et al.
Journal of the American Heart Association’Green Coffee and Tea Consumption and Cardiovascular Disease Mortality Among People with and Without Hypertension’Published December 21, 2022DOI: 10. 1161/JAHA. 122. 026477 Authors: Masayuki Teramoto, Kazumasa Yamagishi, Isao Muraki, Akiko Tamakoshi, and Hiroyasu Iso.
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