(Reuters) – The following is a summary of some of the most recent clinical studies on the new coronavirus and efforts to remedy and vaccines that oppose COVID-19, the disease caused by the virus.
Coronavirus discovered in central muscle cells
The new coronavirus, which has already been detected in some central tissues, can also invade central muscle cells, or myocytes, as discovered by researchers. Doctors in Brazil discovered the virus in the heart cells of an 11-year-old boy with multistemic inflammation. COVID-19-related syndrome that died of center failure, according to a report in The Lancet Child
The gender in COVID-19 deaths is similar to immune responses
Women’s immune systems could possibly induce more appropriate responses to the coronavirus, a small study suggests, offering a clue as to why COVID-19 has a tendency to be more severe in men. Among the 98 older adults who were most frequently hospitalized with mild to moderate COVID-19, women overall had more “robust” and “sustained” attacks opposed to the virus via the T mobiles of their immune systems, the researchers reported. de Array on Wednesday in Nature. They found that poor T mobile responses in men were associated with poorer outcomes. There were also gender differences in the production of signaling molecules, called chemokines and cytokines, that recruit immune mobiles to sites of inflammation. On average, men had higher degrees of these molecules, however, when women had higher degrees, they tended to do wrong. The effects “provide a vital foundation for the progression of a gender-based technique for the remedy and care of men and women with COVID-19,” the researchers said. Men would possibly gain advantage from treatments that stimulate their T-mobile responses, while women possibly gain benefit from treatments that reduce the signaling molecule response, they said. (go. nature. com/2Ewvxrj)
Hormones would possibly contribute to women’s survival gain advantages in COVID-19
Sex hormones could possibly contribute to gender differences in COVID-19 mortality, new studies suggest. While women have lower COVID-19 death rates than men, the difference is narrower in older men and women. Levels of the female hormone estradiol, which are naturally higher in younger women, could contribute to this pattern. The researchers studied the electronic fitness records of nearly 37,000 COVID-19 patients from 17 countries, comparing pre- and postmenopausal women and looking at the use of estradiol in contraceptive or hormone replacement therapy (HRT). Contraceptive drugs have not been linked to a significant effect on COVID-19 death threat. But in women over 50, those who received HRT with estradiol had a two-thirds lower threat of death from coronavirus than non-users in this age group. The examination does not prove that HRT has caused relief in the threat. In their report published Monday in medRxiv ahead of peer review, the researchers cautioned that hormones can have side effects and that women should not start using them on their own. Researchers are requesting large prospective trials to test the theory that estradiol treatment could possibly help decrease the threat of death in older women from COVID-19. (bit. ly/34EtFrt)
Food additives can make dentist visits safer in the face of a pandemic
Scientists could possibly have a solution to the danger dentists and their patients face from the coronavirus pandemic. Mists generated through the water used in dentists’ equipment can also bring exhaled coronavirus debris into the air. Mixing water with a small amount of an FDA-approved food additive called polyacrylic acid can markedly eliminate or even save it, the researchers reported in the journal Physics of Fluid on Tuesday. “What was unexpected was that the first experiment in my lab absolutely demonstrated the concept,” said co-author Alexander Yarin of the University of Illinois at Chicago in a press release. “It was amazing that these fabrics were able to so gently and completely remove aerosolization from dental equipment. ” Aerosol mist occurs when water encounters immediate vibrations from a dental tool or centrifugal force from a drill, breaking the water into tiny droplets and propelling them into the air, the researchers say. The polymer suppresses those explosions because the polymer’s giant molecules stretch like rubber bands, pulling the droplets back and preventing them from spreading through the air. (bit. ly/2YElwzv)
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