A new study letter published online in the Annals of the American Thoracic Society examines asthma as a significant threat to COVID-19 severe enough to warrant hospitalization and intubation.
According to the Centers for Disease Control and Prevention, others with asthma are at increased risk of hospitalization and other serious effects of COVID-19, as well as the main threat of fitness disorders such as obesity, high blood pressure and diabetes.
In “Asthma in COVID-19 Hospitalizations: An Overestimated Risk Factor?”, Fernando Holguin, MD, MPH, and Co-Authors, The Prevalence of Asthma in Hospitalized COVID-19 Patients, As Reported in 15 Studies peer-reviewed, with the prevalence of asthma in the corresponding population.
They also correlated the prevalence of asthma in the United States with the average prevalence of four-year asthma in influenza-related hospitalizations in the United States.
In addition, they analyzed the medical records of 436 COVID-19 patients admitted to the University of Colorado Hospital to assess the likelihood that asthma patients are intubated more than patients without asthma.
CDC exposes others with asthma to a greater threat of COVID-related hospitalization.However, many studies abroad show a low number of asthmatics among patients hospitalized by COVID-19.These effects defy speculation that asthma is a threat factor.”
Researchers conducted a specific review of the english clinical literature to identify studies that reported asthma in patients hospitalized for COVID-19 infection.
Three independent reviewers agreed to include 15 studies in research and, using local patient knowledge hospitalized by COVID-19, conducted statistical research for the dating between asthma prestige and intubation, once they took into account age, sex and body mass.(BMI) of patients.
The authors stated: “We found that the proportion of asthma among patients hospitalized with COVID-19 is similar to that of the prevalence of asthma in the population of each site examined.This is in stark contrast to influenza, in which asthmatics account for more than 20, which coincides with the percentage of hospitalized in the United States.”
“Using the knowledge of our hospital, we also observed that among patients with COVID-19, those with asthma, who had a prevalence rate of 12 percent, did not seem more likely to be intubated than non-asthmatic patients,” they said.Additional.
Dr. Holguin and colleagues, that the corticosteroid inhalers used by many other people with asthma make it difficult for coronaviruses to enter their airways.
Specifically, these Americans would possibly have decreased degrees of expression of ACE2, a protein that binds to SARS-CoV-2, the virus caused by COVID-19.People with allergy-related asthma may also have decreased expression of ACE2, whether or not they use corticosteroids.
”The contribution of ACE2 receptors’ EXPRESSION grades to COVID-19 sensitivity is not yet clear, however, in fact it will be further studied,’ Dr Holguin said.Holguin adds that the threat of asthma-COVID-intubation dating is further studied.
American Thoracic Society
Broadhurst, R.et coll. (2020) Asthma in COVID-19-related hospitalizations: an overrated factor?. Annals of the American Thoracic Society.doi.org/10.1513/AnnalsATS.202006-613RL.
News-Medical.net – An AZoNetwork site
Owned and operated by AZoNetwork, © 2000-2020